Reaktion #11389

Reaktionsgleichung

1-(2′,4′-difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid

3,5-dimethylpiperidine

→

titled product

Ausbeute 43.0%

1-(2′,4′-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3′,5′-dimethylpiperidin-1-yl)-4-oxo-quinoline-3-carboxylic acid

Ausbeute 43.0%

Reaktionsbedingungen

Vorschrift

The condensation of with 1-(2′,4′-difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid with 3,5-dimethylpiperidine in a similar manner as described in example 1 gave the titled product. Yield 43%, m.p 224–26° C., C23H21F3N2O3, m/z 431. (M+1)

Quelle