Reaktion #11388

Reaktionsgleichung

5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid

5-amino-2-methyl-pyrrolidine

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titled product

Ausbeute 40.0%

5-Amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(5′-amino-2′-methyl-pyrrolidin-1-yl)-4-oxo-quinoline-3-carboxylic acid

Ausbeute 40.0%

Reaktionsbedingungen

Vorschrift

The condensation of 5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid with 5-amino-2-methyl-pyrrolidine in a similar manner as described in example 1 gave the titled product. Yield 40%, m.p 224–30° C., C18H20F2N4O3, m/z 379. (M+1)

Quelle