Reaktion #11372

Reaktionsgleichung

compound

2-(5-Amino-2-propoxyphenyl)-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one

4-methyl-1-piperazinesulfonyl chloride

pyridine

→

2-[5-(4-Methylpiperazin-1-yl-sulfonylamino)-2-propoxy-phenyl]-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one

Reaktionsbedingungen

Vorschrift

150 mg (0.408 mmol) of the compound from example 44A are treated with 576 mg (2.45 mmol) of 4-methyl-1-piperazinesulfonyl chloride in 6.6 ml (81.6 mmol) of pyridine for 3.5 hours.

Quelle