Reaktion #1135806

Reaktionsgleichung

1-methoxy-2-methyl-3-aminobenzene

triphosgene

→

1-methoxy-3-isocyanato-2-methylbenzene

Ausbeute 95.3%

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwith heating
2. 2
   Temperaturunder reflux for three hours
3. 3
   Temperaturto cool
4. 4
   Einengenwere concentrated under reduced pressure

Vorschrift

A mixture of 1-methoxy-2-methyl-3-aminobenzene 15.0 g, triphosgene 48.7 g and toluene 350 mL was stirred with heating under reflux for three hours. The reaction mixtures after standing to cool were concentrated under reduced pressure to give 1-methoxy-3-isocyanato-2-methylbenzene 17.0 g.

Quelle