Reaktion #1119902

Reaktionsgleichung

3,4-dichloroaniline

ethyl 1-(3,4-dichlorophenyl)-1,4-dihydro-4-oxo-7-(4- pyridinyl)-3-quinolinecarboxylate

4-fluoroaniline

→

1-(3,4-Dichlorophenyl)-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeprepared

Vorschrift

The starting acid was prepared by hydrolysis of ethyl 1-(3,4-dichlorophenyl)-1,4-dihydro-4-oxo-7-(4- pyridinyl)-3-quinolinecarboxylate (tan solid, m.p. 238°-240 ° C. when recrystallized from toluene), in turn prepared according to the procedures of Example 1, parts (e) and (f), substituting 3,4-dichloroaniline for the 4-fluoroaniline of part (e).

Quelle