Reaktion #1118027

Reaktionsgleichung

1-bromo-2-methoxynaphthalene

β-naphthol

aluminum chloride

2-acetyl-5-bromo-6-methoxynaphthalene

→

2-Acetyl-6-methoxynaphthalene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeobtained as in example 1a),
2. 2
   Sonstigeat -10° C
3. 3
   Sonstigeis crystallized by isopropyl alcohol
4. 4
   Sonstige19 Grams of product are obtained with a yield equal to 38.7%

Vorschrift

42 Ml of β-naphthol and 16.2 g of anhydrous aluminum chloride are added to the solution of 2-acetyl-5-bromo-6-methoxynaphthalene obtained as in example 1a), while keeping the temperature at -10° C. The reaction mixture is kept for 48 hours under stirring at room temperature and then it is worked as in example 1 with the only difference that the product is crystallized by isopropyl alcohol. 19 Grams of product are obtained with a yield equal to 38.7% calculated on the basis of the starting material 1-bromo-2-methoxynaphthalene.

Quelle