Reaktion #1115127

ord-33681630cd1e4562bb0fdf76d4bde71a

Reaktionsgleichung

O=[N+]([O-])c1ncccc1O
2-nitro-3-hydroxypyridine
O=C([O-])[O-].[K+].[K+]
potassium carbonate
CI
methyl iodide
→
COc1cccnc1[N+](=O)[O-]
title compound
Ausbeute 97.4%
COc1cccnc1[N+](=O)[O-]
3-methoxy-2-nitropyridine
Ausbeute 97.4%

Edukte

O=[N+]([O-])c1ncccc1O
2-nitro-3-hydroxypyridine
O=C([O-])[O-].[K+].[K+]
potassium carbonate
CI
methyl iodide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe similar reaction

Vorschrift

The similar reaction as described in Reference Example 9 by using 2-nitro-3-hydroxypyridine (7.0 g), potassium carbonate (6.91 g) and methyl iodide (4.67 ml) gave the title compound (7.5 g) as crystalline powders.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08735401B2uspto-grants-2014_05