Reaktion #1112436

Reaktionsgleichung

10-bromodecane-1-ol

trimethylacetyl chloride

→

2,2-dimethyl-propionic acid 10-bromodecyl ester

Ausbeute 85.0%

Lösungsmittel

pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe reaction was quenched by the addition of dilute hydrochloric acid
2. 2
   Filtrationfiltered through silica
3. 3
   Sonstigeto provide 2,2-dimethyl-propionic acid 10-bromodecyl ester

Vorschrift

2,2-dimethyl-propionic acid 10-bromodecyl ester was prepared in 85% yield by treatment of 10-bromodecane-1-ol with trimethylacetyl chloride in the presence of pyridine and 4-dimethylaminopyridine at room temperature in dithlcromethane. After 18 hrs, the reaction was quenched by the addition of dilute hydrochloric acid worked up and filtered through silica to provide 2,2-dimethyl-propionic acid 10-bromodecyl ester.

Quelle