Reaktion #1109

ord-70baa8bcab424511a56acfca39fce88b

Reaktionsgleichung

CCOc1c(NC2CCC(=O)CC2)ccnc1C
4-(4-oxocyclohexylamino)-3-ethoxy-2-methylpyridine
[Cl-].c1ccc([P+](CCCC2CCCCC2)(c2ccccc2)c2ccccc2)cc1
3-cyclohexylpropyltriphenylphosphonium chloride
→
CCOc1c(NC2CCC(=CCCC3CCCCC3)CC2)ccnc1C
4-[4-(3-Cyclohexylpropylidene)cyclohexylamino]-3-ethoxy-2-methylpyridine
Ausbeute 42.0%

Edukte

CCOc1c(NC2CCC(=O)CC2)ccnc1C
4-(4-oxocyclohexylamino)-3-ethoxy-2-methylpyridine
[Cl-].c1ccc([P+](CCCC2CCCCC2)(c2ccccc2)c2ccccc2)cc1
3-cyclohexylpropyltriphenylphosphonium chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePreparation

Vorschrift

Preparation was carried out analogously to Example 27 from 4-(4-oxocyclohexylamino)-3-ethoxy-2-methylpyridine and 3-cyclohexylpropyltriphenylphosphonium chloride. Yield: 42%

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05723450uspto-grants-1998_03