Reaktion #1106682

Reaktionsgleichung

C-Benzo[1,3]dioxol-2-yl-methylamine

sulfamide

→

title compound

(Benzo[1,3]dioxol-2-ylmethyl)sulfamide

Lösungsmittel

dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe solution was heated
2. 2
   Temperaturto reflux overnight
3. 3
   EinengenThe reaction was concentrated
4. 4
   Sonstigethe residue was chromatographed (2% to 10% acetone in dichloromethane)

Vorschrift

C-Benzo[1,3]dioxol-2-yl-methylamine (2.94 g, 19.4 mmol) and sulfamide (3.74 g, 38.9 mmol) were combined in dry dioxane (50 mL) and the solution was heated to reflux overnight. The reaction was concentrated and the residue was chromatographed (2% to 10% acetone in dichloromethane) to yield the title compound as a white solid.

Quelle