Reaktion #1103535

ord-5dc10445a84e4827a831e449c91222df

Reaktionsgleichung

CCCCCC(CC)Cc1nc(C)c2c(=O)[nH]c(-c3ccccc3OCCC)nn12
2-(2-propoxyphenyl)-5-methyl-7-(2-ethylheptyl)-3H-imidazo[5,1-f]-[1,2,4]-triazin-4-one
CCCCCC(CC)Cc1nc(C)c2c(=O)[nH]c(-c3ccccc3OCCC)nn12
2-(2-Propoxyphenyl)-5-methyl-7-(2-ethylheptyl)-3H-imidazo[5,1-f][1,2,4]triazin-4-one
O=S(=O)(Cl)Cl
sulphonyl chloride
→
CCCCCC(CC)Cc1nc(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)Cl)ccc3OCCC)nn12
4-Propoxy-3-(5-methyl-4-oxo-7-(2-ethylheptyl)-3,4-dihydro-imidazo[5,1-f][1,2,4]triazin-2-yl)-benzenesulphonyl chloride

Edukte

CCCCCC(CC)Cc1nc(C)c2c(=O)[nH]c(-c3ccccc3OCCC)nn12
2-(2-propoxyphenyl)-5-methyl-7-(2-ethylheptyl)-3H-imidazo[5,1-f]-[1,2,4]-triazin-4-one
CCCCCC(CC)Cc1nc(C)c2c(=O)[nH]c(-c3ccccc3OCCC)nn12
2-(2-Propoxyphenyl)-5-methyl-7-(2-ethylheptyl)-3H-imidazo[5,1-f][1,2,4]triazin-4-one
O=S(=O)(Cl)Cl
sulphonyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The preparation is carried out analogously to the procedure of Example 27A using 1.4 g (3.41 mmol) of 2-(2-propoxyphenyl)-5-methyl-7-(2-ethylheptyl)-3H-imidazo[5,1-f]-[1,2,4]-triazin-4-one (Example 20A). This gives 1.4 g (80.6%) of sulphonyl chloride as a white foam which is directly reacted further.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06476029B1uspto-grants-2002_11