Reaktion #1102772
ord-ac71c2d1f954428e83ef1b08523cb610
Reaktionsgleichung
product
2-{[2-fluoro-6-(trifluoromethyl)benzoyl]amino}-4,4,6,6-tetramethyl-4,6-dihydrothieno[2,3-c]furan-3-carboxylic acid
propylamine
→
title compound
2-{[2-fluoro-6-(trifluoromethyl)benzoyl]amino}-4,4,6,6-tetramethyl-N-propyl-4,6-dihydrothieno[2,3-c]furan-3-carboxamide
Edukte
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
The title compound was prepared from the product of Example 45A and propylamine using the procedure described in Example 2B. 1H NMR (DMSO-d6, 300 MHz) δ 0.85 (t, J=7.3 Hz, 3H), 1.42-1.49 (m, 2H), 1.44 (s, 6H), 1.48 (s, 6H), 3.08-3.14 (m, 2H), 7.67-7.8 (m, 3H), 8.05 (t, J=5.4 Hz, 1H), 11.54 (br s, 1H). MS (ESI+) m/z 473 (M+H)+. Anal. calcd. for C22H24F4N2O3S: C, 55.92; H, 5.12; N, 5.93. Found: C, 55.39; H, 4.65; N, 5.69.