Reaktion #1097

ord-7b37c31faaef4c5bb1868f6f9352f189

Reaktionsgleichung

COc1c(Cl)ccnc1C
4-chloro-3-methoxy-2-methylpyridine
CC(C)(C)c1ccc(CON)cc1
O-(4-tert-butylbenzyl)hydroxylamine
→
COc1c(NOCc2ccc(C(C)(C)C)cc2)ccnc1C
4-[O-(4-tert-Butylbenzyl)hydroxylamino]-3-methoxy-2-methylpyridine
Ausbeute 80.0%

Edukte

COc1c(Cl)ccnc1C
4-chloro-3-methoxy-2-methylpyridine
CC(C)(C)c1ccc(CON)cc1
O-(4-tert-butylbenzyl)hydroxylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared analogously to Example 1 from 4-chloro-3-methoxy-2-methylpyridine and O-(4-tert-butylbenzyl)hydroxylamine. Yield: 80%; m.p.: 113° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05723450uspto-grants-1998_03