Reaktion #1096970

Reaktionsgleichung

4-(2-Methoxy-phenyl)-thiazol-2-ylamine

benzoyl chloride

→

N-[4-(2-Methoxy-phenyl)-thiazol-2-yl]-benzamide

Lösungsmittel

pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigepurified by reverse-phase preparative liquid chromatography (11.4 mg, 0.0367 mmol, 18.4%)

Vorschrift

4-(2-Methoxy-phenyl)-thiazol-2-ylamine (41.3 mg, 0.200 mmol) and benzoyl chloride (28.1 mg, 0.200 mmol) were dissolved in 1 mL of pyridine. The reaction mixture was stirred at room temperature overnight and then purified by reverse-phase preparative liquid chromatography (11.4 mg, 0.0367 mmol, 18.4%). ESI-MS m/z calc. 310.1, found 311.2 (M+1)+ Retention time 3.55 minutes.

Quelle