Reaktion #10912
ord-85ee76f1be514947a55c08761ca008f0
Reaktionsgleichung
cyanamide
1-(4-isothiocyanatophenyl)-4-cyclopropylmethylpiperazine
1-(4-Isothiocyanatophenyl)-4-(1-cyclopropylmethyl)piperazine
2-bromo-1-(3-methoxyphenyl)ethanone
→
{4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-methoxy-phenyl)-methanone
Edukte
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
This compound was prepared from cyanamide, 1-(4-isothiocyanatophenyl)-4-cyclopropylmethylpiperazine (of Example 14G) and 2-bromo-1-(3-methoxyphenyl)ethanone (Aldrich) following the procedure used in Example 24 Mass spectrum (ES) MH+=464.