Reaktion #10852

ord-ffec451764134a1db4236c62aaba0bd9

Reaktionsgleichung

CC(=O)CCC(=O)O
levulinic acid
CC(C)N=C=NC(C)C
DIC
ClCCl
DCM
→
CCN(C(C)C)C(C)C
DIEA

Edukte

CC(=O)CCC(=O)O
levulinic acid
—
anhydride
CC(C)N=C=NC(C)C
DIC
ClCCl
DCM

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

addition of activated levulinic acid (activated as the symmetric anhydride with 0.5 equivalents of DIC in DCM for 5-10 min)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07094871B2uspto-grants-2006_08