Reaktion #1076739

ord-8e99ff4366cd44c59d1a3dbbe70495c2

Reaktionsgleichung

CC1=Nc2ccccc2C1(C)C
2,3,3-trimethylindolenine
O=C(O)CCCCCBr
6-bromohexanoic acid
→
CC1[NH+](CCCCCC(=O)O)c2ccccc2C1(C)C.[Br-]
N-(5-carboxypentyl)-2,3,3-trimethylindolinium bromide

Edukte

CC1=Nc2ccccc2C1(C)C
2,3,3-trimethylindolenine
O=C(O)CCCCCBr
6-bromohexanoic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

N-(5-carboxypentyl)-2,3,3-trimethylindolinium bromide was prepared by the process set forth in Example IA with 2,3,3-trimethylindolenine and 6-bromohexanoic acid to produce 2.43 grams (71.2 percent yield) of yellow crystals. 1H and 13C NMR spectra indicated the following:

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06458165B1uspto-grants-2002_10