Reaktion #1074523

Reaktionsgleichung

1,12-Dodecanediol

1,12-dibromododecane

→

title compound

12-Bromododecan-1-ol

Lösungsmittel

hydrogen bromide

—

petroleum ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was evaporated under reduced pressure
2. 2
   Sonstigethe crude oil obtained
3. 3
   Filtrationwas filtered through a pad of silica gel
4. 4
   WaschenElution with petroleum ether (b.p. 40-60° C.)
5. 5
   Sonstigegave a colourless fraction
6. 6
   WaschenThe silica gel was then eluted with acetone

Vorschrift

1,12-Dodecanediol (50 g, 0.25 mol) in hydrogen bromide 48% (220 ml) was continuously extracted with petroleum ether (b.p. 80-100° C.) (300 ml) for 18 hours. The solvent was evaporated under reduced pressure and the crude oil obtained was filtered through a pad of silica gel. Elution with petroleum ether (b.p. 40-60° C.) gave a colourless fraction containing 1,12-dibromododecane. The silica gel was then eluted with acetone to give the title compound as a pale yellow oil after evaporation of the solvent. The title compound crystallised upon cooling and was recrystallised from petroleum ether (b.p. 40-60° C.).

Quelle