Reaktion #10708

Reaktionsgleichung

3,4-dimethoxythiophene

(S)-1,2-octanediol

→

2-n-hexyl-2,3-dihydro-thieno[3,4-b][1,4]dioxine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigepurified to a purity of 99.69%
2. 2
   Sonstigea specific rotation of −100°
3. 3
   Sonstigeat 25° C.

Vorschrift

Chiral 2-n-hexyl-2,3-dihydro-thieno[3,4-b][1,4]dioxine was synthesized by transetherification of 3,4-dimethoxythiophene with (S)-1,2-octanediol and purified to a purity of 99.69% as described in INVENTION EXAMPLE 1. It was characterized by GC-MS and 1H-NMR-spectroscopy, and exhibited a specific rotation of −100° at 25° C. and 436 nm in hexane.

Quelle