Reaktion #10700

Reaktionsgleichung

maleimide

HCOH

NaOH

→

hydroxymethylmaleimide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigereacted at 40° C. for 2 hours
2. 2
   SonstigeAs a result, a white crystal of hydroxymethylmaleimide precipitates
3. 3
   FiltrationThis white crystal is filtered under reduced pressure
4. 4
   Sonstigedried at normal temperature under vacuum

Vorschrift

24 Parts of maleimide (manufactured by Aldrich Corporation), 21 parts of 35% HCOH (manufactured by Wako Pure Chemical Industries, Ltd.) and 0.7 parts of a 5% aqueous NaOH solution are placed in a reactor and reacted at 40° C. for 2 hours. As a result, a white crystal of hydroxymethylmaleimide precipitates. This white crystal is filtered under reduced pressure and then dried at normal temperature under vacuum. The crude crystal of hydroxymethylmaleimide obtained in this manner is recrystallized from ethyl acetate to obtain 22 parts of hydroxymethylmaleimide.

Quelle