Reaktion #10685

Reaktionsgleichung

2-(2-bromoethoxy)tetrahydro-2H-pyran

compound

trans-4-[(4-cyano-5-isoquinolyl)oxy]cyclohexylamine hydrochloride

→

title compound

Trans-1-[(4-cyano-5-isoquinolyl)oxy]-4-[(2-hydroxyethyl)amino]cyclohexane hydrochloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigea deprotection reaction

Vorschrift

According to the method of Example 144, an alkylation reaction with 2-(2-bromoethoxy)tetrahydro-2H-pyran and a deprotection reaction were performed by using the compound of Example 134 to obtain the title compound.

Quelle