Reaktion #1064604

Reaktionsgleichung

2-hydroxyethyl phenyl selenide

thionyl chloride

2-hydroxyethyl phenyl selenide

→

2-Chloroethylphenyl Selenide

Lösungsmittel

CH2Cl2

CH2Cl2

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction mixture was refluxed for 1 h
2. 2
   SonstigeThe solvent was evaporated off
3. 3
   Sonstigethe remaining product transferred to a separatory funnel
4. 4
   workup.ADDITIONTwenty ml of water was added to the separatory funnel
5. 5
   SonstigeThe CHCl3 layer was removed from the separatory funnel
6. 6
   Trocknendried with sodium sulfate
7. 7
   Sonstigeremoved from the product by rotary evaporation

Vorschrift

One gram of the resulting 2-hydroxyethyl phenyl selenide was dissolved in 15 ml of CH2Cl2. One ml of thionyl chloride was dissolved in 5 ml of CH2Cl2 and was added to the solution of the 2-hydroxyethyl phenyl selenide. The reaction mixture was refluxed for 1 h. The solvent was evaporated off and the remaining product transferred to a separatory funnel using CHCl3. Twenty ml of water was added to the separatory funnel and was made weakly basic with 5% aqueous NaHCO3. The CHCl3 layer was removed from the separatory funnel, dried with sodium sulfate and removed from the product by rotary evaporation and then in vacuo.

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