Reaktion #1062922

Reaktionsgleichung

4-(4-propylphenyl)-phenylcyclohexane

cyclohexane

toluene

formic acid

→

3-(4-(4-(4-propylphenyl)phenyl)cyclohexyl)propanal

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturheating the mixture
2. 2
   Temperaturunder reflux for 5 hours
3. 3
   Waschenwashing the reaction mixture with water after completion of the stirring
4. 4
   Trocknendrying over anhydrous magnesium sulfate
5. 5
   Einengenconcentrating under reduced pressure
6. 6
   Sonstigeisolating the resulting yellow oil

Vorschrift

This cyclohexane derivative (11.8 g, 30 mmols) was dissolved in toluene (100 ml), followed by adding formic acid (5 ml), heating the mixture under reflux for 5 hours, washing the reaction mixture with water after completion of the stirring, drying over anhydrous magnesium sulfate, concentrating under reduced pressure and isolating the resulting yellow oil, to obtain 3-(4-(4-(4-propylphenyl)phenyl)cyclohexyl)propanal. This product is used in the subsequent reaction without any purification.

Quelle