Reaktion #1055372

Reaktionsgleichung

hydrazine hydrate

1,4-dichlorophthalazine

→

1-chloro-4-hydrazinophthalazine hydrochloride

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThis reaction, mixture
2. 2
   workup.WAITleft
3. 3
   Temperaturto cool
4. 4
   Filtrationthe product was collected by filtration
5. 5
   Sonstigedried under vacuum

Vorschrift

To a stirred solution of hydrazine hydrate (40 ml) in ethanol (120 mL) at 80° C. was added 1,4-dichlorophthalazine (20 g). This reaction, mixture was stirred at 80° C. for 0.5 hours, then left to cool and the product was collected by filtration and dried under vacuum to give 1-chloro-4-hydrazinophthalazine hydrochloride (14.6 g). 1H NMR (250 MHz, DMSO)•4.64 (2H, vbs), 7.2 (1H, vbs), 7.92 (4H, bm).

Quelle