Reaktion #1054532

Reaktionsgleichung

5-butyl-oxazolidin-2,4-dione sodium salt

2-hydroxyhexanoic acid amide

dimethyl carbonate

sodium methylate

2 -hydroxyhexanoic acid amide

→

5-butyl-oxazolidin-2,4-dione

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigereacted at from 60 to 70° C. for 2 hours
2. 2
   workup.ALIQUOTThereafter, a part of the reaction solution was sampled

Vorschrift

To this solution, dimethyl carbonate (74 g, 0.82 mol) and 30% sodium methylate (147 g, 0.82 mol) were again added and reacted at from 60 to 70° C. for 2 hours. Thereafter, a part of the reaction solution was sampled and the components of the reaction solution were analyzed by HPLC, as a result, the concentration of 2 -hydroxyhexanoic acid amide was 0 mass % in the solution and the concentration of 5-butyl-oxazolidin-2,4-dione sodium salt as the objective product was 27.5% in the solution. From these analysis values, the conversion of 2-hydroxyhexanoic acid amide was 100% and the yield in terms of 5-butyl-oxazolidin-2,4-dione was 94.1%.

Quelle