Reaktion #10491

Reaktionsgleichung

methanesulfonyl chloride

2-(5-bromo-benzothiazol-2-yl)-ethanol

Et3N

→

Methanesulfonic acid 2-(5-bromo-benzothiazol-2-yl)-ethyl ester

Lösungsmittel

CH2Cl2

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenby concentrating under vacuum

Vorschrift

To a mixture of 2-(5-bromo-benzothiazol-2-yl)-ethanol (0.94 g, 3.6 mmol) in 10 mL CH2Cl2, Et3N (0.99 g, 9.8 mmol), was added methanesulfonyl chloride (0.46 g, 4.0 mmol) dropwise at room temperature. The reaction was worked up by concentrating under vacuum and then used in the next step, Example 1C.

Quelle