Reaktion #1046

Reaktionsgleichung

di-t-butylphosphonate

di-t-butyl 2,3,3-trifluoro-2-propenylphosphonate

HCl

→

2,3,3-trifluoro-2-propenylphosphonic acid

Ausbeute 45.8%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThe solution was concentrated
2. 2
   workup.DISSOLUTIONthe residue was redissolved in 10 mL of water
3. 3
   Waschenwashed with 10 mL of ether
4. 4
   SonstigeEvaporation of the aqueous layer

Vorschrift

The above di-t-butylphosphonate (0.5 g) was dissolved in 3 mL of methanol and treated with 0.5 mL, of 3N HCl and allowed to stand at r.t. for 30 min. The solution was concentrated and the residue was redissolved in 10 mL of water and washed with 10 mL of ether. Evaporation of the aqueous layer gave 0.14 g of 2,3,3-trifluoro-2-propenylphosphonic acid as a yellow oil.

Quelle