Reaktion #1012802

Reaktionsgleichung

methyl 1-methyl-8-nitro-1,2-dihydroquinoline-7-carboxylate

→

methyl 8-amino-1-methyl-1,2,3,4-tetrahydroquinoline-7-carboxylate

Lösungsmittel

MeOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe resulting mixture was filtered through celite
2. 2
   Einengenconcentrated

Vorschrift

To a solution of methyl 1-methyl-8-nitro-1,2-dihydroquinoline-7-carboxylate (1.25 g, 5.04 mmol) in degassed MeOH (25 mL) at rt was added Pd/C (125 mg). The mixture was stirred under 1 atm H2 for 16 h. The resulting mixture was filtered through celite and concentrated to afford methyl 8-amino-1-methyl-1,2,3,4-tetrahydroquinoline-7-carboxylate in pure form.

Quelle