Reaktion #1010

Reaktionsgleichung

hydrochloride

1-benzyl-4-chloro-1H-imidazo[4,5-c]pyridine

3-quinuclidinol

→

title compound

Ausbeute 48.6%

3-(1-Benzyl-1H-imidazo[4,5-c]pyridin-4-yloxy)-1-aza-bicyclo[2,2,2]octane

Ausbeute 48.6%

Reaktionsbedingungen

Vorschrift

Following the procedure of Example 1, 1-benzyl-4-chloro-1H-imidazo[4,5-c]pyridine (0.78 g, 3.2 mmol) was treated with 3-quinuclidinol (0.44 g, 3.5 mmol) to give 0.52 g (39%) of the title compound as the hydrochloride, 2.5 hydrate: mp 162°-183° C.

Quelle