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99728

CN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(NC4CCCCC4NS(C)(=O)=O)n3)ccc21
Reaction #186219
DOI: 10.1039/C8SC04228D
CC1(C)CCCNc2ccc(Nc3ncc(Cl)c(NC4CCCCC4NS(C)(=O)=O)n3)cc21
Reaction #208672
DOI: 10.1039/C8SC04228D
CC1(C)CCC(=O)Nc2ccc(Nc3ncc(Cl)c(NC4CCCCC4NS(C)(=O)=O)n3)cc21
Reaction #222574
DOI: 10.1039/C8SC04228D
CN(C1CCCCC1Nc1nc(Nc2ccc3c(c2)C(C)(C)CCC(=O)N3)ncc1Cl)S(C)(=O)=O
Reaction #288995
DOI: 10.1039/C8SC04228D
CN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(NC4CCCCC4N(C)S(C)(=O)=O)n3)ccc21
Reaction #918956
DOI: 10.1039/C8SC04228D
CC1(C)CCC(=O)Nc2ccc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)cc21
Reaction #1128049
solid
Ausbeute 19.0%DOI: 10.6084/m9.figshare.5104873.v1
CN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)ccc21
Reaction #1128053
N-{(1R,2R)-2-[5-Chloro-2-(1,5,5-trimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-cyclohexyl}-methanesulfonamide
Ausbeute 20.0%DOI: 10.6084/m9.figshare.5104873.v1
CCN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)ccc21
Reaction #1128057
N-{(1R,2R)-2-[5-Chloro-2-(1-ethyl-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-cyclohexyl}-methanesulfonamide
Ausbeute 38.4%DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)CCCNc2ccc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)cc21
Reaction #1128063
N-{(1R,2R)-2-[5-Chloro-2-(5,5-dimethyl-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-cyclohexyl}-methanesulfonamide
Ausbeute 17.2%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #1128810
solids
Ausbeute 100.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #1128812
foam
Ausbeute 54.0%DOI: 10.6084/m9.figshare.5104873.v1
CN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4N(C)S(C)(=O)=O)n3)ccc21
Reaction #1128817
N-{(1R,2R)-2-[5-Chloro-2-(1,5,5-trimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-cyclohexyl}-N-methyl-methanesulfonamide
Ausbeute 54.4%DOI: 10.6084/m9.figshare.5104873.v1
CCN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(NC4CCCCC4NS(C)(=O)=O)n3)ccc21
Reaction #1228973
DOI: 10.1039/C8SC04228D
CCN(C1CCCCC1Nc1nc(Nc2ccc3c(c2)C(C)(C)CCC(=O)N3)ncc1Cl)S(C)(=O)=O
Reaction #1659799
DOI: 10.1039/C8SC04228D
CC1(C)CCC(=O)Nc2ccc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)cc21
Reaction #1774357
solid
Ausbeute 19.0%DOI: 10.6084/m9.figshare.5104873.v1
CN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)ccc21
Reaction #1774361
N-{(1R,2R)-2-[5-Chloro-2-(1,5,5-trimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-cyclohexyl}-methanesulfonamide
Ausbeute 20.0%DOI: 10.6084/m9.figshare.5104873.v1
CCN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)ccc21
Reaction #1774365
N-{(1R,2R)-2-[5-Chloro-2-(1-ethyl-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-cyclohexyl}-methanesulfonamide
Ausbeute 38.4%DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)CCCNc2ccc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)cc21
Reaction #1774371
N-{(1R,2R)-2-[5-Chloro-2-(5,5-dimethyl-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-cyclohexyl}-methanesulfonamide
Ausbeute 17.2%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #1775152
solids
Ausbeute 100.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #1775154
foam
Ausbeute 54.0%DOI: 10.6084/m9.figshare.5104873.v1
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