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CCNC(=O)N1CCN(c2ccc(NC(=O)c3cc(=O)c4cc(OC)cc(N5CCN(C)CC5)c4o3)cc2)CC1
Reaction #192028
DOI: 10.1039/C8SC04228D
COc1cc(N2CCN(C)CC2)c2oc(C(=O)Nc3ccc(N4CCN(C(=O)C(C)C)CC4)cc3)cc(=O)c2c1
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COc1cc(N2CCN(C)CC2)c2oc(C(=O)Nc3ccc(N4CCN(C(=O)N5CCOCC5)CC4)cc3)cc(=O)c2c1
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COc1cc(N2CCNCC2)c2oc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1
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COc1cc(N2CCN(C)CC2)c2oc(C(=O)Nc3ccc(N4CCN(S(=O)(=O)N(C)C)CC4)cc3)cc(=O)c2c1
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CCC(=O)N1CCN(c2ccc(NC(=O)c3cc(=O)c4cc(OC)cc(N5CCN(C)CC5)c4o3)cc2)CC1
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COc1cc(N2CCCN(C)CC2)c2[nH]c(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1
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COc1cc(N2CCN(C)CC2)c2oc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1
Reaction #907601
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COc1cc(N2CCNCC2)c2oc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1
Reaction #916662
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COc1cc(N2CCN(C)CC2)c2oc(C(=O)Nc3ccc(N4CC(C)OC(C)C4)cc3)cc(=O)c2c1
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COc1cc(N2CCN(C)CC2)c2oc(C(=O)O)cc(=O)c2c1
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COc1cc(N2CCN(C)CC2)c2oc(C(=O)O)cc(=O)c2c1.Cl
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6-methoxy-8-(4-methyl-1-piperazinyl)-4-oxo-4H-chromene-2-carboxylic acid hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(c2cccc3c(=O)cc(C(=O)Nc4ccc(N5CCOCC5)cc4)oc23)CC1
Reaction #1269155
crude product
DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(c2cccc3c(=O)cc(C(=O)Nc4ccc(N5CCNCC5)cc4)oc23)CC1
Reaction #1269159
solid
Ausbeute 76.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(N2CCN(C)CC2)c2oc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1
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6-Methoxy-8-(4-methyl-piperazin-1-yl)-4-oxo-4H-chromene-2-carboxylic acid (4-morpholin-4-yl-phenyl)-amide
DOI: 10.6084/m9.figshare.5104873.v1
CCC(=O)N1CCN(c2ccc(NC(=O)c3cc(=O)c4cc(OC)cc(N5CCN(C)CC5)c4o3)cc2)CC1
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6-Methoxy-8-(4-methyl-piperazin-1-yl)-4-oxo-4H-chromene-2-carboxylic acid [4-(4-propionyl-piperazin-1-yl)-phenyl]-amide
DOI: 10.6084/m9.figshare.5104873.v1
CCS(=O)(=O)N1CCN(c2ccc(NC(=O)c3cc(=O)c4cc(OC)cc(N5CCN(C)CC5)c4o3)cc2)CC1
Reaction #1269162
6-Methoxy-8-(4-methyl-piperazin-1-yl)-4-oxo-4H-chromene-2-carboxylic acid [4-(4-ethane sulfonyl-piperazin-1-yl)-phenyl]-amide
DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(N2CCN(C)CC2)c2oc(C(=O)Nc3ccc(N4CCN(C(=O)N(C)C)CC4)cc3)cc(=O)c2c1
Reaction #1269163
4-[4-({1-[6-Methoxy-8-(4-methyl-piperazin-1-yl)-4-oxo-4H-chromen-2-yl]-methanoyl}-amino)-phenyl]-piperazine-1-carboxylic acid dimethylamide
DOI: 10.6084/m9.figshare.5104873.v1
CCNC(=O)N1CCN(c2ccc(NC(=O)c3cc(=O)c4cc(OC)cc(N5CCN(C)CC5)c4o3)cc2)CC1
Reaction #1269164
4-[4-({1-[6-Methoxy-8-(4-methyl-piperazin-1-yl)-4-oxo-4H-chromen-2-yl]-methanoyl}-amino)-phenyl]-piperazine-1-carboxylic acid ethylamide
DOI: 10.6084/m9.figshare.5104873.v1
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