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886872

COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2c(F)cccc2F)cn1
Reaction #224003
DOI: 10.1039/C8SC04228D
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(N)cn1
Reaction #374790
DOI: 10.1039/C8SC04228D
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2ccc(F)cc2)cn1
Reaction #1206323
DOI: 10.1039/C8SC04228D
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(N)cn1
Reaction #1729455
5-(5-methoxy-2-trifluoromethyl-benzoimidazol-1-yl)-pyrazin-2-ylamine
Ausbeute 40.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2c(F)cccc2F)cn1
Reaction #1729456
Compound 1
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NCc2ccccc2C)cn1
Reaction #1729457
product
Ausbeute 46.5%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2ccccc2Br)cn1
Reaction #1729458
final product
Ausbeute 29.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2ccc(F)cc2)cn1
Reaction #1729459
Compound 86
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(N)cn1
Reaction #2002211
5-(5-methoxy-2-trifluoromethyl-benzoimidazol-1-yl)-pyrazin-2-ylamine
Ausbeute 40.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2c(F)cccc2F)cn1
Reaction #2002212
Compound 1
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NCc2ccccc2C)cn1
Reaction #2002213
product
Ausbeute 46.5%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2ccccc2Br)cn1
Reaction #2002214
final product
Ausbeute 29.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2ccc(F)cc2)cn1
Reaction #2002215
Compound 86
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(N)cn1
Reaction #2275989
5-(5-methoxy-2-trifluoromethyl-benzoimidazol-1-yl)-pyrazin-2-ylamine
Ausbeute 40.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2c(F)cccc2F)cn1
Reaction #2275990
2,6-Difluoro-N-[5-(5-methoxy-2-trifluoromethyl-benzoimidazol-1-yl)-pyrazin-2-yl]-benzamide
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NCc2ccccc2C)cn1
Reaction #2275991
product
Ausbeute 46.5%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2ccccc2Br)cn1
Reaction #2275992
final product
Ausbeute 29.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(NC(=O)c2ccc(F)cc2)cn1
Reaction #2275993
crude product
DOI: 10.6084/m9.figshare.5104873.v1