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876588

COc1cc2c(Nc3nc(-c4ccccc4)cs3)cnc(CNC(=O)OC(C)(C)C)c2cc1OC
Reaction #42945
[6,7-dimethoxy-4-(4-phenyl-thiazol-2-ylamino)isoquinolin-1-ylmethyl]carbamic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1
COc1cc2c(Nc3nc(-c4ccccc4)cs3)cnc(CN)c2cc1OC.Cl
Reaction #42946
(1-aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-(4-phenyl-thiazol-2-yl)amine hydrochloride salt
Ausbeute 71.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc2c(Nc3nc(C)cs3)cnc(CNC(=O)OC(C)(C)C)c2cc1OC
Reaction #42947
[6,7-dimethoxy-4-(4-methyl-thiazol-2-ylamino)isoquinolin-1-ylmethyl]carbamic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1
COc1cc2c(Nc3nc(C)cs3)cnc(CN)c2cc1OC.Cl
Reaction #42948
(1-aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-(4-methyl-thiazol-2-yl)amine hydrochloride salt
Ausbeute 75.0%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1csc(Nc2cnc(CNC(=O)OC(C)(C)C)c3cc(OC)c(OC)cc23)n1
Reaction #42949
2-[1-(tert-butoxycarbonylamino-methyl)-6,7-dimethoxy-isoquinolin-4-ylamino]thiazole-4-carboxylic acid ethyl ester
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1csc(Nc2cnc(CN)c3cc(OC)c(OC)cc23)n1.Cl
Reaction #42950
2-(1-aminomethyl-6,7-dimethoxy-isoquinolin-4-ylamino)thiazole-4-carboxylic acid ethyl ester hydrochloride salt
Ausbeute 93.0%DOI: 10.6084/m9.figshare.5104873.v1
Cl
Reaction #271154
DOI: 10.1039/C8SC04228D
Cl
Reaction #378447
DOI: 10.1039/C8SC04228D
Cl
Reaction #905790
DOI: 10.1039/C8SC04228D