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860903

CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCNC(=O)CCCCC[C@@H]1NC(=O)N[C@@H]1C)OC)N(C)C(=O)[C@@H](NC(=O)C(C)(C)N)C(C)C
Reaction #162003
#257
Ausbeute 53.1%DOI: 10.6084/m9.figshare.5104873.v1
CCN(CC)CCC(NC(=O)C1(N)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(Cl)cc1
Reaction #173750
DOI: 10.1039/C8SC04228D
CCc1ccc(NC(=O)C2(N)CCN(S(=O)(=O)c3ccc(C)cc3)CC2)cc1
Reaction #173810
DOI: 10.1039/C8SC04228D
Cc1ccc(-c2ccc(CC(NC(=O)C3(NC(=O)OC(C)(C)C)CCOCC3)C(N)=O)cc2)cc1C#N
Reaction #180142
DOI: 10.1039/C8SC04228D
CCN(CC)CCc1ccc(OC)c(C2(N3CC(O)CC3C(=O)N(C)C)C(=O)N(S(=O)(=O)c3ccc(OC)cc3OC(F)(F)F)c3ccc(Cl)cc32)c1
Reaction #180858
DOI: 10.1039/C8SC04228D
COc1cccc(CN(C)C(=O)C=Cc2cnc3c(c2)CNC(C)(C)C(=O)N3)c1OCC(C)C
Reaction #181312
DOI: 10.1039/C8SC04228D
CN1C(=O)Cc2ccc(-c3ccc(CC(NC(=O)C4(NC(=O)OC(C)(C)C)CCOCC4)C(N)=O)cc3)cc21
Reaction #197080
DOI: 10.1039/C8SC04228D
NC1(C(=O)NC(CCO)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]cnc23)CC1
Reaction #202066
DOI: 10.1039/C8SC04228D
CNC(=O)C1(N(C)Cc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CN(C(=O)OC(C)(C)C)C1
Reaction #202212
DOI: 10.1039/C8SC04228D
CC1(C)C(=O)NC(=O)N1CCNc1ncc(Br)c(-c2cc3cc(N)ccc3s2)n1
Reaction #212635
DOI: 10.1039/C8SC04228D
CC1(C)C(=O)N(c2ccc(F)c(-c3cccs3)c2)C(=O)N1Cc1ccc(F)cc1Br
Reaction #223239
DOI: 10.1039/C8SC04228D
COc1ccc(S(=O)(=O)N2C(=O)C(c3cc(CCN4CCCC4)ccc3OC)(N3CC(O)CC3C(=O)N(C)C)c3cc(Cl)ccc32)c(OC(F)(F)F)c1
Reaction #232714
DOI: 10.1039/C8SC04228D
CCCOc1c(CN(C)C(=O)C=Cc2cnc3c(c2)CNCC(=O)N3)cccc1C(C)C
Reaction #246599
DOI: 10.1039/C8SC04228D
CN(C)C(=O)CC(NC(=O)C1(N)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(Cl)cc1
Reaction #247887
DOI: 10.1039/C8SC04228D
CN1C(=O)N(CC(CS(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C(=O)O)C(=O)C1(C)C
Reaction #252147
DOI: 10.1039/C8SC04228D
CN1CCN(C(=O)C(C)(C)NC(=O)OCc2ccccc2)CC1
Reaction #255856
DOI: 10.1039/C8SC04228D
CS(=O)(=O)NCCC(NC(=O)C1(N)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(Cl)cc1
Reaction #256439
DOI: 10.1039/C8SC04228D
CCN(CC)Cc1ccc(OC)c(C2(N3CC(O)CC3C(=O)N(C)C)C(=O)N(S(=O)(=O)c3ccc(OC)cc3OC(F)(F)F)c3ccc(Cl)cc32)c1
Reaction #256784
DOI: 10.1039/C8SC04228D
CCCc1cc(N2CCN(CCN3C(=O)NC(C)(c4ccc(OC(C)C)cc4)C3=O)CC2)ncc1C(O)(C(F)(F)F)C(F)(F)F
Reaction #261585
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)NC1(C(=O)NC(CO)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1
Reaction #262794
DOI: 10.1039/C8SC04228D
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