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839964

OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O
Reaction #7438
Gal
DOI: 10.6084/m9.figshare.5104873.v1
CCc1[nH]c(C(=O)N[C@H]2CCN(c3cccc(C(=O)OC)n3)C[C@H]2OC)nc1Cl
Reaction #72027
title compound
Ausbeute 120.9%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1cc(N2CC[C@H](N)[C@H](OC)C2)ncn1
Reaction #72056
title compound
Ausbeute 71.8%DOI: 10.6084/m9.figshare.5104873.v1
CCc1[nH]c(C(=O)N[C@H]2CCN(c3cc(C(=O)OC)ncn3)C[C@H]2OC)nc1Cl
Reaction #72057
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1ccc(N2CCC[C@@H](Oc3ccccc3OCC)C2)nc1
Reaction #88179
ethyl (R)-6-(3-(2-ethoxyphenoxy)piperidin-1-yl)nicotinate
Ausbeute 60.9%DOI: 10.6084/m9.figshare.5104873.v1
CCOc1ccccc1O[C@@H]1CCCN(c2ccc(C(=O)O)cn2)C1
Reaction #88180
(R)-6-(3-(2-ethoxyphenoxy)piperidin-1-yl)nicotinic acid
Ausbeute 98.8%DOI: 10.6084/m9.figshare.5104873.v1
CCOc1ccccc1O[C@@H]1CCCN(c2ncc(C(=O)OC)cc2F)C1
Reaction #88181
methyl (R)-6-(3-(2-ethoxyphenoxy)piperidin-1-yl)-5-fluoronicotinate
Ausbeute 66.8%DOI: 10.6084/m9.figshare.5104873.v1
CCOc1ccccc1O[C@@H]1CCCN(c2ncc(C(=O)O)cc2F)C1
Reaction #88182
(R)-6-(3-(2-ethoxyphenoxy)piperidin-1-yl)-5-fluoronicotinic acid
Ausbeute 81.6%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #94836
hydrochloride salt
DOI: 10.6084/m9.figshare.5104873.v1
CCCCN(CCCCO)c1ccc(C=Cc2ccc(C=O)s2)c(OCc2ccccc2)c1
Reaction #172515
red crystal
Ausbeute 70.1%DOI: 10.6084/m9.figshare.5104873.v1
CCCCN(CCCCO)c1ccc(C=Cc2ccc(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(C)C)s2)c(OCc2ccccc2)c1
Reaction #172516
dark brown crystal
Ausbeute 56.4%DOI: 10.6084/m9.figshare.5104873.v1
CCCCN(CCCCO)c1ccc(C=Cc2ccc(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(C)C(F)(F)F)s2)c(OCc2ccccc2)c1
Reaction #172517
dark brown crystal
Ausbeute 73.8%DOI: 10.6084/m9.figshare.5104873.v1
CCCCN(CCCCO)c1ccc(C=Cc2ccc(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(c3ccccc3)C(F)(F)F)s2)c(OCc2ccccc2)c1
Reaction #172518
dark brown crystal
Ausbeute 60.9%DOI: 10.6084/m9.figshare.5104873.v1
O=C1OC2(CN3CCC2CC3)CN1c1ccc(-c2cccnc2)s1
Reaction #179302
DOI: 10.1039/C8SC04228D
COC(=O)c1cc(N2CCC(N)C(OC)C2)ncn1
Reaction #179576
DOI: 10.1039/C8SC04228D
COc1ccc(CNc2ncnc3c2ccn3C2OC(CN(C(C)C)C3CC(CCC(=O)OCc4ccccc4)C3)C3OC(C)(C)OC32)c(OC)c1
Reaction #187894
DOI: 10.1039/C8SC04228D
CCOC(=O)C(C)(Cc1ccc(OCCC2CN(Cc3ccc(C(F)(F)F)cc3)C(=O)N2Cc2ccc(OC)cc2)cc1)Oc1ccccc1
Reaction #194745
DOI: 10.1039/C8SC04228D
CCCCCc1ccc(S(=O)(=O)NC(CC(=O)OCc2ccccc2)C[N+](C)(C)C)cc1
Reaction #198710
DOI: 10.1039/C8SC04228D
CN(C)CC(=O)Nc1cnc(Nc2cnc(C#N)cn2)cc1OCC1CCNCC1
Reaction #212939
DOI: 10.1039/C8SC04228D
COC(=O)CCC(=O)Nc1ncc(Oc2cc(I)c(OC)cc2C(C)C)c(N)n1
Reaction #226474
DOI: 10.1039/C8SC04228D
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