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819615

CN(c1ccccc1-c1ccc2cnc(Nc3ccc4c(c3)N(S(C)(=O)=O)CCC4)nn12)S(C)(=O)=O
Reaction #182040
DOI: 10.1039/C8SC04228D
COc1cc(C2(O)CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1
Reaction #185117
DOI: 10.1039/C8SC04228D
CN1CCCC1COc1cc(Nc2ncc3ccc(-c4ccccc4N(C)S(C)(=O)=O)n3n2)ccc1Cl
Reaction #200995
DOI: 10.1039/C8SC04228D
COc1cc(CN2CCC(O)CC2)ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1
Reaction #236054
DOI: 10.1039/C8SC04228D
COc1cc(CN2CCOCC2)ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1
Reaction #260243
DOI: 10.1039/C8SC04228D
CN(c1ccccc1-c1ccc2cnc(Nc3ccc4nc(CO)[nH]c4c3)nn12)S(C)(=O)=O
Reaction #404395
DOI: 10.1039/C8SC04228D
CN1CCN(C)C(c2ccc(Nc3ncc4ccc(-c5ccccc5N(C)S(C)(=O)=O)n4n3)cc2)C1=O
Reaction #766933
DOI: 10.1039/C8SC04228D
COc1cc(C2(O)CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1
Reaction #1349301
4-Hydroxy-4-(4-{7-[2-(methanesulfonyl-methyl-amino)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino}-3-methoxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1
CN1CCCC1COc1cc(Nc2ncc3ccc(-c4ccccc4N(C)S(C)(=O)=O)n3n2)ccc1Cl
Reaction #1349357
N-(2-{2-[4-Chloro-3-(1-methyl-pyrrolidin-2-ylmethoxy)-phenylamino]-pyrrolo[2,1-f][1,2,4]triazin-7-yl}-phenyl)-N-methyl-methanesulfonamide
DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #1349401
foam
Ausbeute 55.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #1349414
solid
Ausbeute 31.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #1349419
foam
Ausbeute 53.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(CN2CCOCC2)ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1
Reaction #1349486
N-{2-[2-(2-Methoxy-4-morpholin-4-ylmethyl-phenylamino)-pyrrolo[2,1-f][1,2,4]triazin-7-yl]-phenyl}-N-methyl-methanesulfonamide
Ausbeute 45.1%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #1349492
solid
Ausbeute 32.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #1349495
solid
Ausbeute 72.0%DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(c2ncc3ccc(-c4ccccc4N(C)S(C)(=O)=O)n3n2)CC1
Reaction #1349503
N-Methyl-N-{2-[2-(4-methyl-piperazin-1-yl)-pyrrolo[2,1-f][1,2,4]triazin-7-yl]-phenyl}-methanesulfonamide
DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(CN2CCN(C)CC2)ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1
Reaction #1349504
N-(2-{2-[2-Methoxy-4-(4-methyl-piperazin-1-ylmethyl)-phenylamino]-pyrrolo[2,1-f][1,2,4]triazin-7-yl}-phenyl)-N-methyl-methanesulfonamide
Ausbeute 30.0%DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(CN2CCN(C)CC2)ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1
Reaction #1653726
DOI: 10.1039/C8SC04228D
COc1c(Nc2ncc3ccc(-c4ccccc4N(C)S(C)(=O)=O)n3n2)cccc1C(=O)N1CCN(C)CC1
Reaction #2226153
DOI: 10.1039/C8SC04228D