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802265

CC1(C)OB(c2ccc(C(=O)N3C[C@H](O)[C@@H](O)C3)cc2)OC1(C)C
Reaction #66284
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CCCN(CCC)C(=O)C1=Cc2ccc(-c3ccc(C(=O)N4C[C@H](O)[C@@H](O)C4)cc3)cc2N=C(NC(=O)OC(C)(C)C)C1
Reaction #66285
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CCCN(CCCO)C(=O)C1=Cc2ccc(-c3ccc(C(=O)N4CC[C@H](O)C4)cc3)cc2N=C(N)C1
Reaction #66298
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)OB(c2ccc(C(=O)N3CCOCC3)cc2)OC1(C)C
Reaction #85797
title compound
Ausbeute 81.0%DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(c2ccc(-c3cc4nccnc4c(NC[C@@H]4CN(C(=O)C(F)F)CCO4)n3)cc2)CC1
Reaction #85911
(R)-2,2-difluoro-1-(2-((7-(4-(4-methylpiperazin-1-yl)phenyl)pyrido[4,3-b]pyrazin-5-ylamino)methyl)morpholino)ethanone
DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(C(=O)c2ccc(-c3cnc4c(n3)N(Cc3c(F)ccc(F)c3Cl)CCN4)cc2)CC1
Reaction #167723
{4-[8-(2-chloro-3,6-difluorobenzyl)-5,6,7,8-tetrahydropyrazino[2,3-b]pyrazin-2-yl]phenyl}(4-methylpiperazin-1-yl)methanone
DOI: 10.6084/m9.figshare.5104873.v1
O=C(c1ccc(-c2cnc3c(n2)N(Cc2c(F)ccc(F)c2Cl)CCN3)cc1)N1CCC(N2CCCC2)CC1
Reaction #167729
{4-[8-(2-chloro-3,6-difluorobenzyl)-5,6,7,8-tetrahydropyrazino[2,3-b]pyrazin-2-yl]phenyl}[4-(pyrrolidin-1-yl)piperidin-1-yl]methanone
DOI: 10.6084/m9.figshare.5104873.v1
CC1(C)OB(c2ccc(C(=O)N3CCC(N4CCCC4)CC3)cc2)OC1(C)C
Reaction #167730
boronic acid
Ausbeute 42.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3cnc4[nH]cc(-c5ccc(C(N)=O)cc5)c4c3)cc2)CC1
Reaction #172234
title compound
Ausbeute 46.0%DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(C(=O)c2ccc(-c3cnc4c(c3)N(C(=O)c3cc(F)ccc3F)CCN4)cc2)CC1
Reaction #179029
DOI: 10.1039/C8SC04228D
CN1CCN(c2ccc(-c3cnc4[nH]cc(C(=O)C5(C)CCCCC5)c4n3)cc2)CC1
Reaction #188968
DOI: 10.1039/C8SC04228D
CC(c1cc(F)c(F)cc1F)N1CCNc2ncc(-c3ccc(C(=O)N4CCN(C)CC4)cc3)cc21
Reaction #192209
DOI: 10.1039/C8SC04228D
CN1CCN(C(=O)c2ccc(-c3cnc4c(c3)N(Cc3cc(F)ccc3F)C(=O)C(C)(C)N4)cc2)CC1
Reaction #225800
DOI: 10.1039/C8SC04228D
CC1(C)OB(c2ccc(C(=O)N3CC(O)C(O)C3)cc2)OC1(C)C
Reaction #234770
DOI: 10.1039/C8SC04228D
CN1CCN(C(=O)c2ccc(-c3cnc4c(c3)N(Cc3cc(F)c(F)cc3F)CCN4)cc2)CC1
Reaction #237176
DOI: 10.1039/C8SC04228D
N#Cc1ccc(-c2ccc(C(=O)N3CCCN(C4CCC4)CC3)cc2)nc1
Reaction #242269
DOI: 10.1039/C8SC04228D
O=C(c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2Cl)C(=O)CN3)cc1)N1CCC(N2CCCC2)CC1
Reaction #245752
DOI: 10.1039/C8SC04228D
O=C(c1ccc(-c2cnc3c(c2)N(C(=O)Cc2cc(F)ccc2F)CCN3)cc1)N1CCC(N2CCCC2)CC1
Reaction #251684
DOI: 10.1039/C8SC04228D
O=C(c1ccc(-c2cnc3c(c2)N(Cc2c(Cl)cccc2Cl)C(=O)CN3)cc1)N1CCC(N2CCCC2)CC1
Reaction #299765
DOI: 10.1039/C8SC04228D
CN1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1
Reaction #303895
title compound
DOI: 10.6084/m9.figshare.5104873.v1
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