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793782

CC(C)N1CCC(NC(=O)c2nc3c(C(=O)O)cccc3n2CCc2ccc(Cl)cc2)CC1
Reaction #46842
1-[2-(4-Chloro-phenyl)-ethyl]-2-(1-isopropyl-piperidin-4-ylcarbamoyl)-1H-benzoimidazole-4-carboxylic acid
DOI: 10.6084/m9.figshare.5104873.v1
COC1CN(C(=O)c2cccc3c2nc(C(=O)NC2CCN(C(C)C)CC2)n3CCc2ccc(Cl)cc2)C1
Reaction #46845
title compound
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2ccc(=O)n(CCN3CCC(NCc4cc5c(cn4)OCCO5)CC3)c2c1
Reaction #68091
1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylmethyl)amino)piperidin-1-yl)ethyl)-7-methoxyquinolin-2(1H)-one
Ausbeute 59.5%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2ncc(=O)n(CCN3CCC(NCc4ccc5c(c4)NC(=O)CO5)CC3)c2c1
Reaction #68097
6-(((1-(2-(7-methoxy-2-oxoquinoxaline-1-(2H)-yl)ethyl)piperidin-4-yl)amino)methyl)-2H-1,4-benzooxazine-3(4H)-one
Ausbeute 19.2%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)c1ccc2c(ccc(=O)n2CCN2CCC(NCc3ccc4c(c3)OCCO4)CC2)c1.Cl
Reaction #68155
1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-6-isopropylquinolin-2(1H)-one hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
Cl.O=c1c(Br)cc2ccccc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1
Reaction #68159
1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-3-bromoquinolin-2(1H)-one hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
Cl.O=c1cc(Cl)c2ccc(Cl)cc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1
Reaction #68192
1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-4,7-dichloroquinolin-2(1H)-one hydrochloride
Ausbeute 133.7%DOI: 10.6084/m9.figshare.5104873.v1
CNC(=O)COc1cccc2c1ccc(=O)n2CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1
Reaction #68206
(1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-2-oxo-1,2-dihydroquinolin-5-yloxy)-N-methylacetamide
Ausbeute 67.5%DOI: 10.6084/m9.figshare.5104873.v1
CNC(=O)COc1cccc2c1ccc(=O)n2CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1.Cl
Reaction #68207
(1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-2-oxo-1,2-dihydroquinolin-5-yloxy)-N-methylacetamide hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
Cl.O=c1cc(Cl)c2ccc(F)cc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1
Reaction #68212
1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-4-chloro-7-fluoroquinolin-2(1H)-one hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc5c(cn4)OCCO5)CC3)c2c1.Cl
Reaction #68258
1-(2-(4-((2,3-dihydro-1,4-dioxino[2,3-c]pyridin-7-yl)methylamino)piperidin-1-yl)ethyl)-7-methoxy-quinoxalin-2(1H)-one hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
O=c1cnc2ccc(Br)cc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1
Reaction #68264
1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-7-bromoquinoxalin-2(1H)-one
Ausbeute 71.5%DOI: 10.6084/m9.figshare.5104873.v1
Cl.O=c1cnc2ccc(Br)cc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1
Reaction #68265
1-(2-(4-((2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-7-bromoquinoxalin-2(1H)-one hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2ncc(=O)n(CCN3CCC(NCc4ccc(C)c(NC(=O)OC(C)(C)C)c4)CC3)c2c1
Reaction #68278
tert-butyl (5-(((1-(2-(7-methoxy-2-oxoquinoxalin-1(2H)-yl)ethyl)piperidin-4-yl)amino)methyl)-2-methylphenyl)carbamate
Ausbeute 81.2%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2ncc(=O)n(CCN3CCC(NCc4ccc(C)c(N)c4)CC3)c2c1.Cl
Reaction #68279
1-(2-(4-((3-amino-4-methylbenzyl)amino)piperidin-1-yl)ethyl)-7-methoxyquinoxalin-2(1H)-one hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1ccc2ncc(=O)n(CCN3CCC(NCc4cc5c(cn4)OCCO5)CC3)c2c1
Reaction #68295
1-(2-(4-((2,3-dihydro-1,4-dioxino[2,3-c]pyridin-7-yl)methylamino)piperidin-1-yl)ethyl)-7-cyanoquinoxalin-2(1H)-one
Ausbeute 49.4%DOI: 10.6084/m9.figshare.5104873.v1
Cl.N#Cc1ccc2ncc(=O)n(CCN3CCC(NCc4cc5c(cn4)OCCO5)CC3)c2c1
Reaction #68296
1-(2-(4-((2,3-dihydro-1,4-dioxino[2,3-c]pyridin-7-yl)methylamino)piperidin-1-yl)ethyl)-7-cyanoquinoxalin-2(1H)-one hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc(OC)c5c(c4)OCCO5)CC3)c2c1
Reaction #68297
7-methoxy-1-(2-(4-((8-methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)methylamino)piperidin-1-yl)ethyl)quinoxalin-2(1H)-one
Ausbeute 51.8%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc(OC)c5c(c4)OCCO5)CC3)c2c1.Cl
Reaction #68298
7-methoxy-1-(2-(4-((8-methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)methylamino)piperidin-1-yl)ethyl)quinoxalin-2(1H)-one hydrochloride
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc5c(cc4Br)OCCO5)CC3)c2c1
Reaction #68303
1-(2-(4-((7-bromo-2,3-dihydro-1,4-benzodioxin-6-yl)methylamino)piperidin-1-yl)ethyl)-7-methoxyquinoxalin-2(1H)-one
Ausbeute 49.6%DOI: 10.6084/m9.figshare.5104873.v1
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