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78596

COc1ccc(CNc2ncnc3c2c(-c2ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc2)nn3[C@@H]2CCCc3c2cnn3S(=O)(=O)c2ccc(C)cc2)c(OC)c1
Reaction #90742
(R)-4-(4-((2,4-dimethoxybenzyl)amino)-1-(1-tosyl-4,5,6,7-tetrahydro-1H-indazol-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)benzamide
Ausbeute 87.4%DOI: 10.6084/m9.figshare.5104873.v1
Nc1ncnc2c1c(-c1ccc(C(=O)Nc3cc(C(F)(F)F)ccn3)cc1)nn2[C@@H]1CCCc2[nH]ncc21
Reaction #90743
title compound
Ausbeute 53.0%DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(C2CCC(n3nc(-c4ccc(C(NCCc5ccccc5)c5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1
Reaction #176278
DOI: 10.1039/C8SC04228D
CN1CCN(C2CCC(n3nc(-c4ccc(C(=O)Nc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1
Reaction #187097
DOI: 10.1039/C8SC04228D
CN1CCN(C2CCC(n3nc(-c4ccc(C(=O)NCCc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1
Reaction #230418
DOI: 10.1039/C8SC04228D
CC(C)n1nc(-c2ccc(CC#N)cc2)c2c(N)ncnc21
Reaction #245439
DOI: 10.1039/C8SC04228D
CC(=O)c1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1
Reaction #325128
BA31
Ausbeute 62.4%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)n1nc(-c2ccc(CC#N)cc2)c2c(N)ncnc21
Reaction #325139
2-(4-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)acetonitrile
DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)c1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1
Reaction #325160
BA31
Ausbeute 62.4%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)n1nc(-c2ccc(CC#N)cc2)c2c(N)ncnc21
Reaction #325171
2-(4-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)acetonitrile
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)n1nc(-c2ccc3c(N)n[nH]c3c2)c2c(N)ncnc21
Reaction #325209
BA154
Ausbeute 70.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)n1nc(-c2ccc(C#N)c(O)c2)c2c(N)ncnc21
Reaction #325210
4-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-hydroxybenzonitrile
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)c1ccc(-c2n[nH]c3ncnc(N)c23)cc1
Reaction #325213
3-(4-tert-butylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
DOI: 10.6084/m9.figshare.5104873.v1
Cc1ccc(-c2n[nH]c3ncnc(N)c23)cc1
Reaction #325228
3-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)c1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1
Reaction #381731
DOI: 10.1039/C8SC04228D
CN1CCN(C2CCC(n3nc(-c4ccc(C(C#N)c5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1
Reaction #400942
DOI: 10.1039/C8SC04228D
CC(C)n1nc(-c2ccc(C#N)c(O)c2)c2c(N)ncnc21
Reaction #407265
DOI: 10.1039/C8SC04228D
COc1cc(-c2nn(-c3cccc(N(C)C(=O)/C=C/CN(C)C4CCC4)c3)c3ncnc(N)c23)ccc1C
Reaction #475620
(E)-N-(3-(4-amino-3-(3-methoxy-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-4-(cyclobutyl(methyl)amino)-N-methylbut-2-enamide
Ausbeute 14.2%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #519344
solid
Ausbeute 44.1%DOI: 10.6084/m9.figshare.5104873.v1
CON=C(c1ccccc1)c1ccc(-c2nn([C@H]3CC[C@@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)cc1
Reaction #519354
cis-{4-{4-amino-1-[4-(4-methylpiperazino)cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-phenyl}(phenyl)methanone O-methyloxime
Ausbeute 73.9%DOI: 10.6084/m9.figshare.5104873.v1
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