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784544

Cn1cc(Br)cc(Nc2cccc(N)n2)c1=O
Reaction #180640
DOI: 10.1039/C8SC04228D
Cn1cc(Br)cc(Nc2cccc(N)n2)c1=O
Reaction #644706
3-(6-amino-pyridin-2-ylamino)-5-bromo-1-methyl-1H-pyridin-2-one
Ausbeute 18.3%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1cc(Nc2cccc(N)n2)c(=O)n(C)c1
Reaction #644707
N-{3-[5-(6-amino-pyridin-2-ylamino)-1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl]-2-methyl-phenyl}-4-tert-butyl-benzamide
Ausbeute 40.4%DOI: 10.6084/m9.figshare.5104873.v1
Cn1cc(Br)cc(Nc2cccc(N)n2)c1=O
Reaction #680089
221a
Ausbeute 48.3%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)OCc1c(-c2cc(Nc3cccc(N)n3)c(=O)n(C)c2)ccnc1N1CCn2c(cc3c2CC(C)(C)C3)C1=O
Reaction #680090
221b
Ausbeute 31.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1cc(Nc2cccc(N)n2)c(=O)n(C)c1
Reaction #749414
DOI: 10.1039/C8SC04228D
Cn1cc(Br)cc(Nc2cccc(N)n2)c1=O
Reaction #1109158
221a
Ausbeute 48.3%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)OCc1c(-c2cc(Nc3cccc(N)n3)c(=O)n(C)c2)ccnc1N1CCn2c(cc3c2CC(C)(C)C3)C1=O
Reaction #1109159
221b
Ausbeute 31.0%DOI: 10.6084/m9.figshare.5104873.v1
Cn1cc(Br)cc(Nc2cccc(N)n2)c1=O
Reaction #1499028
221a
Ausbeute 48.3%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)OCc1c(-c2cc(Nc3cccc(N)n3)c(=O)n(C)c2)ccnc1N1CCn2c(cc3c2CC(C)(C)C3)C1=O
Reaction #1499029
221b
Ausbeute 31.0%DOI: 10.6084/m9.figshare.5104873.v1
C=CC(=O)NCCNc1cccc(Nc2cc(Br)cn(C)c2=O)n1
Reaction #1861819
N-(2-(6-(5-bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-ylamino)pyridin-2-ylamino)ethyl)acrylamide
Ausbeute 65.0%DOI: 10.6084/m9.figshare.5104873.v1
C=CC(=O)NCCNc1cccc(Nc2cc(-c3cc(F)cc(-n4ncc5c6c(sc5c4=O)CCCC6)c3COC(C)=O)cn(C)c2=O)n1
Reaction #1861820
N-[2-[[6-[[5-[5-fluoro-2-(acetoxymethyl)-3-(4-oxo-6,7,8,9-tetrahydrobenzothiopheno[2,3-d]pyridazin-3-yl)phenyl]-1-methyl-2-oxo-3-pyridyl]amino]-2-pyridyl]amino]ethyl]prop-2-enamide
Ausbeute 31.0%DOI: 10.6084/m9.figshare.5104873.v1
C=CC(=O)NCCN(C)c1cccc(Nc2cc(Br)cn(C)c2=O)n1
Reaction #1861834
N-(2-((6-(5-bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-ylamino)pyridin-2-yl)(methyl)amino)ethyl)acrylamide
Ausbeute 22.0%DOI: 10.6084/m9.figshare.5104873.v1
C=CC(=O)NCCN(C)c1cccc(Nc2cc(-c3cc(F)cc(-n4ncc5c6c(sc5c4=O)CCCC6)c3COC(C)=O)cn(C)c2=O)n1
Reaction #1861835
N-[2-[[6-[[5-[5-fluoro-2-(acetoxymethyl)-3-(4-oxo-6,7,8,9-tetrahydrobenzothiopheno[2,3-d]pyridazin-3-yl)phenyl]-1-methyl-2-oxo-3-pyridyl]amino]-2-pyridyl]-methyl-amino]ethyl]prop-2-enamide
Ausbeute 71.7%DOI: 10.6084/m9.figshare.5104873.v1
C=CC(=O)N[C@H]1CCCN(c2cccc(Nc3cc(Br)cn(C)c3=O)n2)C1
Reaction #1861845
(S)—N-(1-(6-(5-bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-ylamino)pyridin-2-yl)piperidin-3-yl)acrylamide
Ausbeute 28.4%DOI: 10.6084/m9.figshare.5104873.v1
C=CC(=O)N[C@H]1CCCN(c2cccc(Nc3cc(-c4cc(F)cc(-n5ncc6c7c(sc6c5=O)CCCC7)c4COC(C)=O)cn(C)c3=O)n2)C1
Reaction #1861846
N-[(3S)-1-[6-[[5-[5-fluoro-2-(acetoxymethyl)-3-(4-oxo-6,7,8,9-tetrahydrobenzothiopheno[2,3-d]pyridazin-3-yl)phenyl]-1-methyl-2-oxo-3-pyridyl]amino]-2-pyridyl]-3-piperidyl]prop-2-enamide
Ausbeute 33.6%DOI: 10.6084/m9.figshare.5104873.v1