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764284

COc1cc(Cl)cc2c1CCC2
Reaction #42221
6-chloro-4-methoxyindane
Ausbeute 68.0%DOI: 10.6084/m9.figshare.5104873.v1
CCc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(=O)OC)c1
Reaction #45373
title compound
DOI: 10.6084/m9.figshare.5104873.v1
OCc1ccc(-c2ccc3nnc(Cc4ccc5ncccc5c4)n3n2)cc1Cl
Reaction #68560
(2-chloro-4-(3-(quinolin-6-ylmethyl)-[1,2,4]-triazolo[4,3-b]pyridazin-6-yl)phenyl)methanol
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(OCc3nnc4ccc(-c5ccc(CO)c(Cl)c5)nn34)ccnc2c1
Reaction #68561
(2-chloro-4-(3-((7-methoxyquinolin-4-yloxy)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)methanol
DOI: 10.6084/m9.figshare.5104873.v1
COc1cnc2c(NCc3nnc4ccc(-c5ccc(C(C)O)c(Cl)c5)nn34)ccnc2c1
Reaction #68562
1-(2-chloro-4-(3-((7-methoxy-1,5-naphthyridin-4-ylamino)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)ethanol
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(OCc3nnc4ccc(-c5ccc(C(C)NC(=O)OC(C)(C)C)c(Cl)c5)nn34)ccnc2c1
Reaction #68565
tert-butyl 1-(2-chloro-4-(3-((7-methoxyquinolin-4-yloxy)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)ethylcarbamate
DOI: 10.6084/m9.figshare.5104873.v1
CC(c1ccc2ncccc2c1)c1nnc2ccc(-c3cnn(C)c3)nn12
Reaction #68571
6-(1-(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)ethyl)quinoline
DOI: 10.6084/m9.figshare.5104873.v1
Nc1ccnc2cccnc12
Reaction #68572
1,5-naphthyridin-4-amine
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N(C[C@@H]1CCc2cc(-c3ccc4c(c3)OC(C)(C)OC4=O)ccc2O1)C[C@@H](COc1ccccc1)O[Si](C)(C)C(C)(C)C
Reaction #75971
desired product
Ausbeute 76.0%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)CC1CCC(c2ccc(-c3ccc(C(=O)Nc4ccc(C(F)(F)F)nc4)cn3)cc2)CC1
Reaction #163267
(4-{4-[5-(6-Trifluoromethyl-pyridin-3-ylcarbamoyl)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid methyl ester
DOI: 10.6084/m9.figshare.5104873.v1
OCc1ccc(-c2ccc3nnc(Cc4ccc5ncccc5c4)n3n2)cc1Cl
Reaction #306357
(2-chloro-4-(3-(quinolin-6-ylmethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)methanol
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(OCc3nnc4ccc(-c5ccc(CO)c(Cl)c5)nn34)ccnc2c1
Reaction #306358
(2-chloro-4-(3-((7-methoxyquinolin-4-yloxy)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)methanol
DOI: 10.6084/m9.figshare.5104873.v1
COc1cnc2c(NCc3nnc4ccc(-c5ccc(C(C)O)c(Cl)c5)nn34)ccnc2c1
Reaction #306359
1-(2-chloro-4-(3-((7-methoxy-1,5-naphthyridin-4-ylamino)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)ethanol
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(OCc3nnc4ccc(-c5ccc(CNC(=O)OC(C)(C)C)c(Cl)c5)nn34)ccnc2c1
Reaction #306360
tert-butyl (2-chloro-4-(3-((7-methoxyquinolin-4-yloxy)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)methylcarbamate
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc2c(OCc3nnc4ccc(-c5ccc(C(C)NC(=O)OC(C)(C)C)c(Cl)c5)nn34)ccnc2c1
Reaction #306363
tert-butyl 1-(2-chloro-4-(3-((7-methoxyquinolin-4-yloxy)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)ethylcarbamate
DOI: 10.6084/m9.figshare.5104873.v1
CC(c1ccc2ncccc2c1)c1nnc2ccc(-c3cnn(C)c3)nn12
Reaction #306370
6-(1-(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)ethyl)quinoline
DOI: 10.6084/m9.figshare.5104873.v1
Nc1ccnc2cccnc12
Reaction #306371
1,5-naphthyridin-4-amine
DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #418255
foam
Ausbeute 95.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #418256
solid
Ausbeute 56.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #418257
solid
Ausbeute 14.0%DOI: 10.6084/m9.figshare.5104873.v1
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