3-(2,6-dichloropyrimidin-4-yl)-8-oxa-3-azabicyclo[3.2.1]octane

Clc1cc(N2CC3CCC(C2)O3)nc(Cl)n1
Reaction #162592
3-(2,6-dichloro-pyrimidin-4-yl)-8-oxa-3-aza-bicyclo[3.2.1]octane
Ausbeute 83.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
Nc1ccc(-c2cc(N3CC4CCC(C3)O4)nc(Cl)n2)cc1
Reaction #162593
4-[2-chloro-6-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-pyrimidin-4-yl]-phenylamine
Ausbeute 16.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
O=[N+]([O-])c1ccc(-c2nc(Cl)cc(N3CC4CCC(C3)O4)n2)cc1
Reaction #162594
3-[6-chloro-2-(4-nitro-phenyl)-pyrimidin-4-yl]-8-oxa-3-aza-bicyclo[3.2.1]octane
Ausbeute 10.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
Clc1cc(N2CC3CCC(C2)O3)nc(I)n1
Reaction #162595
desired product
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
Oc1nc(Cl)cc(N2CC3CCC(C2)O3)n1
Reaction #162605
title compound
Ausbeute 221.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09