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690281

CCOC(=O)C1C2CCC(C2)C1NCc1ccc(F)c(Cl)c1
Reaction #213510
DOI: 10.1039/C8SC04228D
CCOC(=O)[C@@]1(F)[C@@H]2C[C@@H](NCc3ccc(Cl)c(Cl)c3)[C@@](NC(=O)OC(C)(C)C)(C(=O)OCC)[C@@H]21
Reaction #217691
(1R,2R,3R,5R,6R)-2-t-butoxycarbonylamino-3-(3,4-dichlorobenzylamino)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid diethyl ester
Ausbeute 39.3%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@]1(N)[C@H]2[C@@H](C[C@H]1NCc1ccc(Cl)c(Cl)c1)[C@]2(F)C(=O)OCC
Reaction #217692
(1R,2R,3R,5R,6R)-2-amino-3-(3,4-dichlorobenzylamino)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid diethyl ester
Ausbeute 92.3%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@]1(F)[C@@H]2C[C@@H](NC(=O)c3ccc(Cl)c(Cl)c3)[C@@](NC(=O)OC(C)(C)C)(C(=O)OCC)[C@@H]21
Reaction #217693
(1R,2R,3R,5R,6R)-2-t-butoxycarbonylamino-3-(3,4-dichlorobenzoylamino)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid diethyl ester
Ausbeute 84.5%DOI: 10.6084/m9.figshare.5104873.v1
O=C(NCCCC(NCc1ccc(Cl)cc1)C(=O)NC1CCCC1C(=O)OCC(=O)c1ccccc1)OCc1ccccc1
Reaction #227923
DOI: 10.1039/C8SC04228D
CCOC(=O)C1(F)C2CC(NC(=O)c3ccc(Cl)c(Cl)c3)C(NC(=O)OC(C)(C)C)(C(=O)OCC)C21
Reaction #400455
DOI: 10.1039/C8SC04228D
CCOC(=O)C1CCCC1Nc1ccc(Cl)cc1
Reaction #446284
desired product
DOI: 10.6084/m9.figshare.5104873.v1
OCC1CCCC1Nc1ccc(Cl)cc1
Reaction #446285
desired product
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1NCc1ccc(F)c(Cl)c1
Reaction #511442
(1S,2R,3S,4R)-3-(3-chloro-4-fluoro-benzylamino)-bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester
Ausbeute 77.0%DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]3N(Cc3ccc(F)c(Cl)c3)C1=O)N2
Reaction #511443
(1R,2S,7R,8S)—N-{3-[3-(3-chloro-4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide
Ausbeute 43.0%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1NCc1ccc(F)c(Cl)c1
Reaction #635548
(1S,2R,3S,4R)-3-(3-chloro-4-fluoro-benzylamino)-bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester
Ausbeute 77.0%DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]3N(Cc3ccc(F)c(Cl)c3)C1=O)N2
Reaction #635549
(1R,2S,7R,8S)-N-{3-[3-(3-chloro-4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide
Ausbeute 43.0%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@]1(F)[C@@H]2C[C@@H](NCc3ccc(Cl)c(Cl)c3)[C@@](NC(=O)OC(C)(C)C)(C(=O)OCC)[C@@H]21
Reaction #745710
(1R, 2R, 3R, 5R, 6R)-2-t-butoxycarbonylamino3-(3,4-dichlorobenzylamino)-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid diethyl ester
Ausbeute 39.3%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@]1(N)[C@H]2[C@@H](C[C@H]1NCc1ccc(Cl)c(Cl)c1)[C@]2(F)C(=O)OCC
Reaction #745711
(1R,2R,3R,5R,6R)-2-amino-3-(3,4-dichlorobenzylamino)-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid diethyl ester
Ausbeute 92.3%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@]1(F)[C@@H]2C[C@@H](NC(=O)c3ccc(Cl)c(Cl)c3)[C@@](NC(=O)OC(C)(C)C)(C(=O)OCC)[C@@H]21
Reaction #745712
(1R, 2R, 3R, 5R, 6R)-2-t-butoxycarbonylamino-3-(3,4-dichlorobenzoylamino)-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid diethyl ester
Ausbeute 84.5%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)C1(N)C(NCc2ccc(Cl)c(Cl)c2)CC2C1C2(F)C(=O)OCC
Reaction #753793
DOI: 10.1039/C8SC04228D
CCOC(=O)[C@@H]1CCC[C@@H]1NCc1ccc(F)cn1
Reaction #818428
cis-2-[(5-fluoro-pyridin-2-ylmethyl)-amino]-cyclopentanecarboxylic acid ethyl ester
Ausbeute 52.5%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@H]1CCC[C@H]1NCCC1CC1
Reaction #818471
trans-2-(2-cyclopropylethylamino)-cyclopentanecarboxylic acid ethyl ester
Ausbeute 90.5%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@H]1CCC[C@@H]1NCCC(C)C
Reaction #818498
(1R,2S)-2-(3-methyl-butylamino)-cyclopentanecarboxylic acid ethyl ester
Ausbeute 61.0%DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@H]1CCC[C@@H]1NCCC(C)(C)C
Reaction #818501
(1R,2S)-2-(3,3-dimethyl-butylamino)-cyclopentanecarboxylic acid ethyl ester
Ausbeute 33.7%DOI: 10.6084/m9.figshare.5104873.v1
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