2,2,2-trifluoro-1-[1-(4-hydroxyphenyl)-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]ethanone

COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2c1ccc(OS(=O)(=O)c2ccc(C)cc2)cc1
Reaction #484221
orange oil
Ausbeute 115.4%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2003_08
COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2c1ccc(OCCN2CCCC2)cc1
Reaction #484255
yellow oil
Ausbeute 87.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2003_08
COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2c1ccc(OCCN2CCCC2)cc1
Reaction #886042
DOI: 10.1039/C8SC04228DTest data from https://doi.org/10.1039/C8SC04228D