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51411

Cc1c(-c2ccccc2)c(F)c2oc(C3CC3)nc2c1C#N
Reaction #45724
compound
Ausbeute 92.2%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2oc(C3CC3)nc2c1C#N
Reaction #45725
product
Ausbeute 69.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2cccc(F)c2)c(F)c2oc(C3CC3)nc2c1C#N
Reaction #45726
compound
Ausbeute 72.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2ccccc2F)c(F)c2oc(C3CC3)nc2c1C#N
Reaction #45727
2-Cyclopropyl-7-fluoro-6-(2-fluorophenyl)-5-methyl-1,3-benzoxazole-4-carbonitrile
DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2ccccc2F)c(N2CC[C@H](N(C)C)C2)c2oc(C3CC3)nc2c1C#N
Reaction #45728
2-Cyclopropyl-7-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-6-(2-fluorophenyl)-5-methyl-1,3-benzoxazole-4-carbonitrile
DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2cc(F)cc(F)c2)c(F)c2oc(C3CC3)nc2c1C#N
Reaction #45729
2-Cyclopropyl-6-(3,5-difluorophenyl)-7-fluoro-5-methyl-1,3-benzoxazole-4-carbonitrile
DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2cc(F)cc(F)c2)c(N2CC[C@H](N(C)C)C2)c2oc(C3CC3)nc2c1C#N
Reaction #45730
compound
Ausbeute 16.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2cccc(F)c2F)c(F)c2oc(C3CC3)nc2c1C#N
Reaction #45731
compound
Ausbeute 53.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2cccc(F)c2F)c(N2CC[C@H](N(C)C)C2)c2oc(C3CC3)nc2c1C#N
Reaction #45732
product
Ausbeute 85.4%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2cccc(N)c2)c(F)c2oc(C3CC3)nc2c1C#N
Reaction #45733
6-(3-Aminophenyl)-2-cyclopropyl-7-fluoro-5-methyl-1,3-benzoxazole-4-carbonitrile
DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2cccc(N)c2)c(N2CC[C@H](N(C)C)C2)c2oc(C3CC3)nc2c1C#N
Reaction #45734
6-(3-Aminophenyl)-2-cyclopropyl-7-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-5-methyl-1,3-benzoxazole-4-carbonitrile
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)[C@@H]1C[C@H]1c1nc2c(C#N)c(C)c(-c3ccccc3)c(N3CC[C@H](N(C)C)C3)c2o1
Reaction #45787
compound
Ausbeute 42.0%DOI: 10.6084/m9.figshare.5104873.v1
CN[C@H]1CCN(c2c(-c3ccccc3)c(C)c(C#N)c3nc(C4CC4)oc23)C1
Reaction #45856
compound
Ausbeute 63.0%DOI: 10.6084/m9.figshare.5104873.v1
CCN[C@H]1CCN(c2c(-c3ccccc3)c(C)c(C#N)c3nc(C4CC4)oc23)C1
Reaction #45857
compound
Ausbeute 23.5%DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1c(CBr)c(-c2ccccc2)c(F)c2oc(C3CC3)nc12
Reaction #45858
compound
Ausbeute 82.0%DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1c(CF)c(-c2ccccc2)c(F)c2oc(C3CC3)nc12
Reaction #45859
compound
Ausbeute 59.4%DOI: 10.6084/m9.figshare.5104873.v1
CN[C@H]1CCN(c2c(-c3ccccc3)c(CF)c(C#N)c3nc(C4CC4)oc23)C1
Reaction #45860
compound
Ausbeute 24.0%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)C(C(=O)OC)c1c(-c2ccccc2)c(C)c(C#N)c2nc(C3CC3)oc12
Reaction #45861
compound
Ausbeute 77.4%DOI: 10.6084/m9.figshare.5104873.v1
Cc1c(-c2ccccc2)c(N2CCC[C@H]2CN(C)C)c2oc(C3CC3)nc2c1C#N
Reaction #45899
compound
Ausbeute 20.0%DOI: 10.6084/m9.figshare.5104873.v1
CCNC1CCN(c2c(-c3ccccc3)c(C)c(C#N)c3nc(C4CC4)oc23)C1
Reaction #179028
DOI: 10.1039/C8SC04228D
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