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47479

C[Si](C)(C)CCOCn1c(C2CC2)nc(Br)c1-c1ccnc(NCC2(C#N)CC2)n1
Reaction #622928
1-((4-(4-bromo-2-cyclopropyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)methyl)cyclopropanecarbonitrile
Ausbeute 66.0%DOI: 10.6084/m9.figshare.5104873.v1
C[C@H](N)CNc1nccc(-c2[nH]c(C3(C)CC3)nc2Br)n1
Reaction #622936
(S)—N1-(4-(4-bromo-2-(1-methylcyclopropyl)-1H-imidazol-5-yl)pyrimidin-2-yl)propane-1,2-diamine
Ausbeute 136.0%DOI: 10.6084/m9.figshare.5104873.v1
CC1(c2nc(Br)c(-c3ccnc(NCCC#N)n3)n2COCC[Si](C)(C)C)CC1
Reaction #622938
3-(4-(4-bromo-2-(1-methylcyclopropyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)propanenitrile
Ausbeute 100.0%DOI: 10.6084/m9.figshare.5104873.v1
CC1(c2nc(Br)c(-c3ccnc(NCCC#N)n3)[nH]2)CC1
Reaction #622939
3-(4-(4-bromo-2-(1-methylcyclopropyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)propanenitrile
Ausbeute 95.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #622949
crude residue
DOI: 10.6084/m9.figshare.5104873.v1
C[Si](C)(C)CCOCn1c(C2CC2)nc(Br)c1-c1ccnc(NCC2(C#N)CC2)n1
Reaction #972925
1-((4-(4-bromo-2-cyclopropyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)methyl)cyclopropanecarbonitrile
Ausbeute 66.0%DOI: 10.6084/m9.figshare.5104873.v1
CC1(c2nc(Br)c(-c3ccnc(NCCC#N)n3)n2COCC[Si](C)(C)C)CC1
Reaction #972933
3-(4-(4-bromo-2-(1-methylcyclopropyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)propanenitrile
Ausbeute 100.0%DOI: 10.6084/m9.figshare.5104873.v1
CC1(c2nc(Br)c(-c3ccnc(NCCC#N)n3)[nH]2)CC1
Reaction #972934
3-(4-(4-bromo-2-(1-methylcyclopropyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)propanenitrile
Ausbeute 95.0%DOI: 10.6084/m9.figshare.5104873.v1
C[Si](C)(C)CCOCn1c(C2CC2)nc(-c2cc(Cl)cc(N)c2F)c1-c1ccnc(NCCC#N)n1
Reaction #972943
3-(4-(4-(3-amino-5-chloro-2-fluorophenyl)-2-cyclopropyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)propanenitrile
DOI: 10.6084/m9.figshare.5104873.v1
C[Si](C)(C)CCOCn1c(C2CC2)nc(Br)c1-c1ccnc(NCC2(C#N)CC2)n1
Reaction #1130905
1-((4-(4-bromo-2-cyclopropyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)methyl)cyclopropanecarbonitrile
Ausbeute 66.0%DOI: 10.6084/m9.figshare.5104873.v1
C[C@H](N)CNc1nccc(-c2[nH]c(C3(C)CC3)nc2Br)n1
Reaction #1130913
(S)—N1-(4-(4-bromo-2-(1-methylcyclopropyl)-1H-imidazol-5-yl)pyrimidin-2-yl)propane-1,2-diamine
Ausbeute 136.0%DOI: 10.6084/m9.figshare.5104873.v1
CC1(c2nc(Br)c(-c3ccnc(NCCC#N)n3)n2COCC[Si](C)(C)C)CC1
Reaction #1130915
3-(4-(4-bromo-2-(1-methylcyclopropyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)propanenitrile
Ausbeute 100.0%DOI: 10.6084/m9.figshare.5104873.v1
CC1(c2nc(Br)c(-c3ccnc(NCCC#N)n3)[nH]2)CC1
Reaction #1130916
3-(4-(4-bromo-2-(1-methylcyclopropyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)propanenitrile
Ausbeute 95.0%DOI: 10.6084/m9.figshare.5104873.v1
C[Si](C)(C)CCOCn1c(C2CC2)nc(-c2cc(Cl)cc(N)c2F)c1-c1ccnc(NCCC#N)n1
Reaction #1130925
3-(4-(4-(3-amino-5-chloro-2-fluorophenyl)-2-cyclopropyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)propanenitrile
DOI: 10.6084/m9.figshare.5104873.v1
C[Si](C)(C)CCOCn1c(C2CC2)nc(-c2cc(Cl)cc(N)c2F)c1-c1ccnc(NCCC#N)n1
Reaction #2237823
DOI: 10.1039/C8SC04228D
CC1(c2nc(Br)c(-c3ccnc(NCCC#N)n3)[nH]2)CC1
Reaction #2414430
DOI: 10.1039/C8SC04228D