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CCOC(=O)C1COCCN1CC#CCN1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(Cc2ccc(C)c(C)c2)C1

Reaction #289668

DOI: 10.1039/C8SC04228D

C#CCN1CCOC[C@H]1C(=O)OCC

Reaction #671416

(3S)-3-ethoxycarbonyl-4-(2-propynyl)morpholine

DOI: 10.6084/m9.figshare.5104873.v1

CCOC(=O)[C@@H]1COCCN1CC#CCN1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2ccc(C)c(C)c2)C1

Reaction #671423

(2R)-1-[3,5-bis(trifluoromethyl)benzoyl]-2-(3,4-dimethylbenzyl)-4-[4-((3S)-3-ethoxycarbonylmorpholino)-2-butynyl]piperazine

Ausbeute 20.2%DOI: 10.6084/m9.figshare.5104873.v1

Cc1ccc(C[C@@H]2CN(CC#CCN3CCOC[C@H]3C(=O)O)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C

Reaction #671424

(2R)-1-[3,5-bis(trifluoromethyl)benzoyl]-2-(3,4-dimethylbenzyl)-4-[4-((3S)-3-carboxymorpholino)-2-butynyl]piperazine

Ausbeute 64.7%DOI: 10.6084/m9.figshare.5104873.v1

C#CCN1CCOCC1C(=O)OCC

Reaction #1028401

DOI: 10.1039/C8SC04228D

Cc1ccc(CC2CN(CC#CCN3CCOCC3C(=O)O)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C

Reaction #2244280

DOI: 10.1039/C8SC04228D