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CC(C)(C)OC(=O)NC1CCC(NC(=O)c2cccnc2)CC1
Reaction #187767
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)NC1CCC(NC(=O)c2cc(F)cnc2Cl)CC1
Reaction #584703
{4-[(2-chloro-5-fluoro-pyridine-3-carbonyl)amino]-cyclohexyl}-carbamic acid tert-butyl ester
Ausbeute 39.5%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@H]1CC[C@H](NC(=O)c2cccnc2)CC1
Reaction #809213
N-tert-butoxycarbonyl-trans-4-(3-pyridylcarbonylamino)cyclohexylamine
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@H]1CC[C@@H](NC(=O)c2cc(F)cnc2Cl)CC1
Reaction #811454
{cis-4-[(2-Chloro-5-fluoro-pyridine-3-carbonyl)-amino]-cyclohexyl}-carbamic acid tert-butyl ester
Ausbeute 73.5%DOI: 10.6084/m9.figshare.5104873.v1
CSc1cccc(Oc2ncc(F)cc2C(=O)N[C@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)c1
Reaction #811455
(cis-4-{[-5-fluoro-2-(3-methylsulfanyl-phenoxy)-pyridine-3-carbonyl]-amino}-cyclohexyl)-carbamic acid tert-butyl ester
Ausbeute 53.1%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)NC1CCC(NC(=O)c2ccc(Oc3ccc(C#N)cc3)nc2Oc2ccc(C#N)cc2)CC1
Reaction #1111864
required product
Ausbeute 67.3%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)NC1CCC(NC(=O)c2cc(F)cnc2Cl)CC1
Reaction #1206208
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N[C@H]1CC[C@H](NC(=O)c2cccnc2)CC1
Reaction #1532544
N-tert-butoxycarbonyl-trans-4-(3-pyridylcarbonylamino)cyclohexylamine
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)NC1CCC(NC(=O)c2cc(F)cnc2Cl)CC1
Reaction #1916014
{4-[(2-chloro-5-fluoro-pyridine-3-carbonyl)amino]-cyclohexyl}-carbamic acid tert-butyl ester
Ausbeute 39.5%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@H]1CC[C@H](NC(=O)c2cccnc2)CC1
Reaction #2142300
N-tert-butoxycarbonyl-trans-4-(3-pyridylcarbonylamino)cyclohexylamine
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)NC1CCC(NC(=O)c2cc(F)cnc2Cl)CC1
Reaction #2228658
DOI: 10.1039/C8SC04228D
CSc1cccc(Oc2ncc(F)cc2C(=O)NC2CCC(NC(=O)OC(C)(C)C)CC2)c1
Reaction #2234198
DOI: 10.1039/C8SC04228D