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O

CC(=O)Nc1ccc(C(=O)N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)c2ccccc2C(F)(F)F)cc1
Reaction #2581
title compound
DOI: 10.6084/m9.figshare.5104873.v1
O=C(Nc1ccc(C(=O)N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)c2cccnc2)cc1)c1ccccc1
Reaction #2615
title compound
Ausbeute 71.3%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(-c2cc(-c3nc4ccc(Cl)cc4n3COCC[Si](C)(C)C)c(=O)n(COCC[Si](C)(C)C)n2)cc(C)c1O
Reaction #40552
4-[6-Chloro-1-(2-trimethylsilanylethoxymethyl)-1H-benzimidazol-2-yl]-6-(4-hydroxy-3,5-dimethyl phenyl)-2-(2-trimethylsilanylethoxymethyl)-2H-pyridazin-3-one
DOI: 10.6084/m9.figshare.5104873.v1
C[Si](C)(C)CCOCn1nc(Cl)cc(-c2nc3ccc(C=O)cc3n2COCC[Si](C)(C)C)c1=O
Reaction #40558
6-Chloro-4-(6-formyl-1-(2-trimethylsilanylethoxymethyl)-1H-benz-imidazol-2-yl]-2-(2-trimethylsilanylethoxymethyl)-2H-pyridazin-3-one
DOI: 10.6084/m9.figshare.5104873.v1
CN1CCN(Cc2ccc3nc(-c4cc(Cl)nn(COCC[Si](C)(C)C)c4=O)n(COCC[Si](C)(C)C)c3c2)CC1
Reaction #40559
6-Chloro-4-(6-(4-methylpiperazin-1-ylmethyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzimidazol-2-yl]-2-(2-trimethylsilanylethoxymethyl)-2H-pyridazin-3-one
DOI: 10.6084/m9.figshare.5104873.v1
C[C@H](NC(=O)C(F)(F)F)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1cccc(O)c1
Reaction #41329
product
Ausbeute 42.2%DOI: 10.6084/m9.figshare.5104873.v1
C[C@H](NC(=O)[C@@H](C)O)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccc(C(F)(F)F)cc1
Reaction #41450
(2R)-N-[(1R,2S)-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-[4-(trifluoromethyl)phenyl]propan-2-yl]-2-hydroxy-propanamide
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)c1cccc(Nc2nc3cc(Oc4ccnc(C(=O)NCCNS(=O)(=O)Cc5ccccc5)c4)ccc3n2C)c1
Reaction #41787
4-[2-(3-Isopropyl-phenylamino)-1-methyl-1H-benzoimidazol-5-yloxy]-pyridine-2-carboxylic acid (2-phenylmethanesulfonylamino-ethyl)-amide
DOI: 10.6084/m9.figshare.5104873.v1
CN(C)C(=O)NCc1cc(Oc2ccc3c(ccn3C(=O)Nc3cccc(C(F)(F)F)c3)c2)ncn1
Reaction #73345
title compound
DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc2c(F)c(Oc3ccnc(CO)n3)ccc2n1C(=O)Nc1cccc(C(F)(F)F)c1
Reaction #73404
4-fluoro-5-(2-hydroxymethyl-pyrimidin-4-yloxy)-2-methyl-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide
DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc2c(F)c(Oc3ccnc(CNCCO)n3)ccc2n1C(=O)Nc1cccc(C(F)(F)F)c1
Reaction #73405
4-fluoro-5-{2-[(2-hydroxy-ethylamino)-methyl]-pyrimidin-4-yloxy}-2-methyl-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide
DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc2c(F)c(Oc3ccnc(CS(C)(=O)=O)n3)ccc2n1C(=O)Nc1cccc(C(F)(F)F)c1
Reaction #73406
4-fluoro-5-(2-methanesulfonylmethyl-pyrimidin-4-yloxy)-2-methyl-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide
DOI: 10.6084/m9.figshare.5104873.v1
O=C(CCCBr)NCc1cc(Oc2ccc3c(ccn3C(=O)Nc3ccc(F)c(C(F)(F)F)c3)c2)ncn1
Reaction #73412
title compound
DOI: 10.6084/m9.figshare.5104873.v1
O=C1CCCN1Cc1cc(Oc2ccc3c(ccn3C(=O)Nc3ccc(F)c(C(F)(F)F)c3)c2)ncn1
Reaction #73413
title compound
DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(N)c(OC)n2)c(OC)c1
Reaction #157828
(5R)-5-[(E)-2-(5-amino-6-methoxypyridin-2-yl)-2-(4-tert-butylphenyl)ethenyl]-1-(2,4-dimethoxybenzyl)pyrrolidin-2-one
DOI: 10.6084/m9.figshare.5104873.v1
COc1nc(/C(=C/[C@H]2CCC(=O)N2)c2ccc(C(C)(C)C)cc2)ccc1N
Reaction #157829
(5R)-5-[(E)-2-(5-amino-6-methoxypyridin-2-yl)-2-(4-tert-butylphenyl)ethenyl]pyrrolidin-2-one
Ausbeute 44.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #158169
solid
Ausbeute 32.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #160410
solid
DOI: 10.6084/m9.figshare.5104873.v1
CCCNC(=O)N(C(C)=O)c1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1Cl
Reaction #182877
DOI: 10.1039/C8SC04228D
Cc1cc2c(F)c(Oc3ccnc(CO)n3)ccc2n1C(=O)Nc1cccc(C(F)(F)F)c1
Reaction #186404
DOI: 10.1039/C8SC04228D
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