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376998

CC(C)C[C@@H](C(=O)Nc1ccn(C[C@@H]2COC(C)(C)O2)n1)N1CC(Oc2cccc3c2CCCC3)=CC1=O
Reaction #47341
(S)-4-methyl-2-[2-oxo-4-(5,6,7,8-tetrahydro-naphthalen-1-yloxy)-2,5-dihydro-pyrrol-1-yl]-pentanoic acid [1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl-methyl)-1H-pyrazol-3-yl]-amide
Ausbeute 48.4%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)C[C@@H](C(=O)Nc1ccn(C[C@@H](O)CO)n1)N1CC(Oc2cccc3c2CCCC3)=CC1=O
Reaction #47342
(S)-4-methyl-2-[2-oxo-4-(5,6,7,8-tetrahydro-naphthalen-1-yloxy)-2,5-dihydro-pyrrol-1-yl]-pentanoic acid [1-((R)-2,3-dihydroxy-propyl)-1H-pyrazol-3-yl]-amide
Ausbeute 72.5%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(O)Cn1ccc(NC(=O)C(CC2CCOCC2)N2CC(Oc3ccccc3Br)=CC2=O)n1
Reaction #47699
2-[4-(2-bromo-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-3-(tetrahydro-pyran-4-yl)-propionamide
Ausbeute 35.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C([C@H](O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(N2CCCNC2=O)CC1
Reaction #48501
title compound
DOI: 10.6084/m9.figshare.5104873.v1
O=C([C@H](O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(N2CCCN(CCO)C2=O)CC1
Reaction #48517
title compound
Ausbeute 54.0%DOI: 10.6084/m9.figshare.5104873.v1
O=C1CCN(C2CCN(C(=O)[C@H](O)CS(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2)C(=O)N1
Reaction #48523
title compound
Ausbeute 9.1%DOI: 10.6084/m9.figshare.5104873.v1
O=C([C@H](O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(N2CCC(O)NC2=O)CC1
Reaction #48525
title compound
Ausbeute 66.6%DOI: 10.6084/m9.figshare.5104873.v1
CCN(CCCCC[C@H]1CC[C@H](N(C)S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1)CCO[Si](C)(C)C(C)(C)C
Reaction #53896
trans-N-[4-(5-{[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-ethyl-amino}-pentyl)-cyclohexyl]-N-methyl-4-trifluoromethyl-benzenesulfonamide
Ausbeute 10.2%DOI: 10.6084/m9.figshare.5104873.v1
CCN(CCCCC[C@H]1CC[C@H]([N+](C)([O-])S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1)CCO[Si](C)(C)C(C)(C)C
Reaction #53897
trans-N-[4-(5-{[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-ethyl-amino}-pentyl)-cyclohexyl]-N-methyl-4-trifluoromethyl-benzenesulfonamide N-oxide
Ausbeute 30.7%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(S(=O)(=O)NC(OC2CCCC2)[C@H](O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)c2ccc3ccccc3n2)cc1
Reaction #57453
(2S)-N1-((1S,2R)-1-benzyl-3-(cyclopentyloxy)[(4-methoxyphenyl)sulfonyl]amino-2-hydroxypropyl)-2-[(2-quinolinylcarbonyl)amino]butanediamide
Ausbeute 41.4%DOI: 10.6084/m9.figshare.5104873.v1
COc1ccc(S(=O)(=O)NC(OC2CCCCC2)[C@H](O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)c2ccc3ccccc3n2)cc1
Reaction #57458
(2S)-N1-((1S,2R)-1-benzyl-3-(cyclohexyloxy)[(4-methoxyphenyl)sulfonyl]amino-2-hydroxypropyl)-2-[(2-quinolinylcarbonyl)amino]butanediamide
DOI: 10.6084/m9.figshare.5104873.v1
O=C(NCC1(N2CCN(C3CC3)CC2)CCN(C(=O)COCCN(C2CC2)S(=O)(=O)c2ccccc2C(F)(F)F)CC1)c1ccncc1
Reaction #74288
crude product
Ausbeute 55.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #94836
hydrochloride salt
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)Oc1cc(N2CC3CCC(C2)O3)nc(-c2ccc(N)cc2)n1
Reaction #162599
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)Oc1cc(N2CC3CCC(C2)O3)nc(O)n1
Reaction #162610
title compound
Ausbeute 85.1%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)Oc1cc(N2CC3CCC(C2)O3)nc(Cl)n1
Reaction #162611
title compound
Ausbeute 46.0%DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)Cc1cc(N2CC3CCC(C2)O3)nc(Cl)n1
Reaction #162618
3-(2-chloro-6-(methylsulfonylmethyl)pyrimidin-4-yl)-8-oxa-3-azabicyclo[3.2.1]octane
DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)Cc1cc(N2CC3CCC(C2)O3)nc(-c2ccc(N)cc2)n1
Reaction #162619
desired compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)Nc1nc(Cl)nc(N2CC3CCC(C2)O3)c1N.CN(C)CCC(=O)[O-]
Reaction #162624
6-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-2-chloro-N4-isopropylpyrimidine-4,5-diamine 3-(dimethylamino)propanoate
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)Nc1nc(Cl)nc(N2CC3CCC(C2)O3)c1NC(=O)CCN(C)C
Reaction #162625
N-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-2-chloro-6-(isopropylamino)pyrimidin-5-yl)-3-(dimethylamino)propanamide
DOI: 10.6084/m9.figshare.5104873.v1
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